DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8728 and AT1G51980

DIOPT Version :9

Sequence 1:	NP_610333.1	Gene:	CG8728 / 35748	FlyBaseID:	FBgn0033235	Length:	556	Species:	Drosophila melanogaster
Sequence 2:	NP_175610.1	Gene:	AT1G51980 / 841627	AraportID:	AT1G51980	Length:	503	Species:	Arabidopsis thaliana

Alignment Length:	514	Identity:	164/514 - (31%)
Similarity:	257/514 - (50%)	Gaps:	56/514 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 EVGSGTG--IGQITGGVRTS----DGP-QKVNTPSKEIVTHLPPLTEPLPNLPEAVYAAPLAESA 92
            |..|.|.  :..::||.|.:    |.| |.|:.|        |||.:.:             |.:
plant    33 ETSSSTPAYLSWLSGGSRAALTSLDMPLQGVSLP--------PPLADKV-------------EPS 76

  Fly    93 ITKVTTLPNGLRIASEPRYGQFCTVGLVIDSGPRYEVAYPSGVSHFLEKLAFNSTVNFPNKDAIL 157
            ..::|||||||:||||.......::||.:|.|..||..|..|.:|.||::||.||:| .....::
plant    77 KLQITTLPNGLKIASETTPNPAASIGLYVDCGSIYEAPYFHGATHLLERMAFKSTLN-RTHFRLV 140

  Fly   158 KELEKNGGICDCQSSRDTLIYAASIDSRAIDSVTRLLADVTLRPTLSDQEVSLARRAVNFELETL 222
            :|:|..||.....:||:.:.|........:..:..:|.|....|...|.||:...|.:..|:..|
plant   141 REIEAIGGNTSASASREQMSYTIDALKTYVPEMVEVLIDSVRNPAFLDWEVNEELRKMKVEIAEL 205

  Fly   223 GMRPEQEPILMDMIHAAAFRDNTLGLPKLCPLENLDHINRNVLMNYLKYHHSPKRMVIAGVGVDH 287
            ...|  ...|::.||:|.: ...|..|...|...||.:|..:|..::..:.:..|||:|..||:|
plant   206 AKNP--MGFLLEAIHSAGY-SGPLASPLYAPESALDRLNGELLEEFMTENFTAARMVLAASGVEH 267

  Fly   288 DELVSHVQRYFVEDKAIWETEALEDSGPKQVDTSIAQYTGGLVKEQCEIPIYAAAGLPELAHVIL 352
            :||:...:..         |..|.:..|:....|  ||.||..::.       ..|  |..|..:
plant   268 EELLKVAEPL---------TSDLPNVPPQLAPKS--QYVGGDFRQH-------TGG--EATHFAV 312

  Fly   353 GFE--GCSHQDKDFVPLCVLNIMMGGGGSFSAGGPGKGMYSRLYTKVLNRYHWMYSATAYNHAYG 415
            .||  |.:: :|:.|...||.::||||||||||||||||:|.||.:|||.|..:.|.||:...:.
plant   313 AFEVPGWNN-EKEAVTATVLQMLMGGGGSFSAGGPGKGMHSWLYRRVLNEYQEVQSCTAFTSIFN 376

  Fly   416 DCGLFCVHGSAPPQHMNDMVEVLTREMMGMA-AEPGREELMRSKIQLQSMLLMNLESRPVVFEDV 479
            |.|||.::|.:.||.....:|:..:|:..:| .:..:..|.|:|...:|.:|||||||.:..||:
plant   377 DTGLFGIYGCSSPQFAAKAIELAAKELKDVAGGKVNQAHLDRAKAATKSAVLMNLESRMIAAEDI 441

  Fly   480 GRQVLVTGQRKRPQHFIKEIESVTAADIQRVAQRLLSSPPSVAARGDIHNLPEMSHITN 538
            |||:|..|:||....|:|.::.:|..||.....:::|.|.::.:.||:..:|....|::
plant   442 GRQILTYGERKPVDQFLKSVDQLTLKDIADFTSKVISKPLTMGSFGDVLAVPSYDTISS 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8728	NP_610333.1	PqqL	76..532	CDD:223685	148/458 (32%)
		Peptidase_M16	104..253	CDD:279066	43/148 (29%)
		Peptidase_M16_C	259..461	CDD:282978	68/204 (33%)
AT1G51980	NP_175610.1	PqqL	58..480	CDD:223685	152/467 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	100	1.000	Domainoid score	I2354
eggNOG	1	0.900	-	-		E1_COG0612
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	238	1.000	Inparanoid score	I1094
OMA	1	1.010	-	-		QHG53769
OrthoDB	1	1.010	-	-		D631107at2759
OrthoFinder	1	1.000	-	-		FOG0003938
OrthoInspector	1	1.000	-	-		otm3427
orthoMCL	1	0.900	-	-		OOG6_102381
Panther	1	1.100	-	-	O	PTHR11851
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2236
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	11.880