Protein Alignment CG8728 and UQCRC2

DIOPT Version :9

• Sequence 1: NP_610333.1
• Gene: CG8728 / 35748
• FlyBaseID: FBgn0033235
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_003357.2
• Gene: UQCRC2 / 7385
• HGNCID: 12586
• Length: 453
• Species: Homo sapiens
• Alignment Length: 436
• Identity: 117/436 - (26%)
• Similarity: 196/436 - (44%)
• Gaps: 29/436 - (6%)

  Fly    97 TTLPNGLRIASEPRYGQFCTVGLVIDSGPRYEVAYPSGVSHFLEKLAFNSTVNFPNKDAILKELE 161
            |.|||||.|||...|.....:||.|.:|.|||.....|.:|.| :|..:.|....:...|.:.:|
Human    41 TKLPNGLVIASLENYSPVSRIGLFIKAGSRYEDFSNLGTTHLL-RLTSSLTTKGASSFKITRGIE 104

  Fly   162 KNGGICDCQSSRDTLIYAASIDSRAIDSVTRLLADVTLRPTLSDQEVSLARRAVNFELETLGMRP 226
            ..||.....::|:.:.|........:|.:...|.:||..|.....||:..:..:..:.......|
Human   105 AVGGKLSVTATRENMAYTVECLRGDVDILMEFLLNVTTAPEFRRWEVADLQPQLKIDKAVAFQNP 169

  Fly   227 EQEPILMDMIHAAAFRDNTLGLPKLCPLENLDHINRNVLMNYLKYHHSPKRMVIAGVGVDHDELV 291
            :..  :::.:||||:| |.|..|..||...:..:....|..:::.|.:..||.:.|:||.| .::
Human   170 QTH--VIENLHAAAYR-NALANPLYCPDYRIGKVTSEELHYFVQNHFTSARMALIGLGVSH-PVL 230

  Fly   292 SHVQRYFVEDKAIWETEALEDSGPKQVDTSIAQYTGGLVKEQCEIPIYAAAGLPELAHVILGFEG 356
            ..|...|:..:.     .|..||.|      |.|.||.::||....:..||.:.|.|  :.|
Human   231 KQVAEQFLNMRG-----GLGLSGAK------ANYRGGEIREQNGDSLVHAAFVAESA--VAG--- 279

  Fly   357 CSHQDKDFVPLCVLNIMMGGGGSFSAGGPGKGMYSRLYTKVLNRYHWMYSATAYNHAYGDCGLFC 421
             |.:...|   .||..::|.|.....   |....|.|:..|.......:..:|:|.:|.|.|||.
Human   280 -SAEANAF---SVLQHVLGAGPHVKR---GSNTTSHLHQAVAKATQQPFDVSAFNASYSDSGLFG 337

  Fly   422 VHGSAPPQHMNDMVEVLTREMMGMA-AEPGREELMRSKIQLQSMLLMNLESRPVVFEDVGRQVLV 485
            ::..:......|:::....::..:| ......::..:|.:|::..||::||.....|:||.|.||
Human   338 IYTISQATAAGDVIKAAYNQVKTIAQGNLSNTDVQAAKNKLKAGYLMSVESSECFLEEVGSQALV 402

  Fly   486 TGQRKRPQHFIKEIESVTAADIQRVAQRLLSSPPSVAARGDIHNLP 531
            .|....|...:::|:||..|||...|::.:|...|:||.|::.:.|
Human   403 AGSYMPPSTVLQQIDSVANADIINAAKKFVSGQKSMAASGNLGHTP 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8728	NP_610333.1	PqqL	76..532	CDD:223685	117/436 (27%)
		Peptidase_M16	104..253	CDD:279066	38/148 (26%)
		Peptidase_M16_C	259..461	CDD:282978	45/202 (22%)
UQCRC2	NP_003357.2	PqqL	37..436	CDD:223685	112/422 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0612
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810