Protein Alignment CG8728 and Pmpca

DIOPT Version :9

• Sequence 1: NP_610333.1
• Gene: CG8728 / 35748
• FlyBaseID: FBgn0033235
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_775272.1
• Gene: Pmpca / 66865
• MGIID: 1918568
• Length: 524
• Species: Mus musculus
• Alignment Length: 496
• Identity: 263/496 - (53%)
• Similarity: 347/496 - (69%)
• Gaps: 23/496 - (4%)

  Fly    71 PLTEPLPNLPEAVYAAPLAESAI-TKVTTLPNGLRIASEPRYGQFCTVGLVIDSGPRYEVAYPSG 134
            ||:.|||.:|:.::|....:... ||||||.||||:||:.::|||||||::|:||.|||..|.||
Mouse    42 PLSSPLPGVPKPIFATVDGQEKFETKVTTLDNGLRVASQNKFGQFCTVGILINSGSRYEAKYLSG 106

  Fly   135 VSHFLEKLAFNSTVNFPNKDAILKELEKNGGICDCQSSRDTLIYAASIDSRAIDSVTRLLADVTL 199
            ::||||||||:||..|.:||.||..|||:|||||||:||||.:||.|.||:.:|:|..|||||.|
Mouse   107 IAHFLEKLAFSSTARFDSKDEILLTLEKHGGICDCQTSRDTTMYAVSADSKGLDTVVDLLADVVL 171

  Fly   200 RPTLSDQEVSLARRAVNFELETLGMRPEQEPILMDMIHAAAFRDNTLGLPKLCPLENLDHINRNV 264
            .|.|:|:|:.:.|.||.||||.|.|||:.||:|.:|||.||||:||:||.:.||:||:..|:|.|
Mouse   172 HPRLTDEEIEMTRMAVQFELEDLNMRPDPEPLLTEMIHEAAFRENTVGLHRFCPVENIAKIDREV 236

  Fly   265 LMNYLKYHHSPKRMVIAGVGVDHDELVSHVQRYFVEDKAIWETEALEDSGPKQVDTSIAQYTGGL 329
            |.:|||.:::|.|||:|||||:|:.||...::|.|..:..|..     .|...||.|:||||||:
Mouse   237 LHSYLKNYYTPDRMVLAGVGVEHEHLVECARKYLVGAEPAWGA-----PGTVDVDRSVAQYTGGI 296

  Fly   330 VKEQCEI--------PIYAAAGLPELAHVILGFEGCSHQDKDFVPLCVLNIMMGGGGSFSAGGPG 386
            :|.:.::        ||      |||.|:::|.|.||..:.||:|..|||:||||||||||||||
Mouse   297 IKVERDMSNVSLGPTPI------PELTHIMVGLESCSFLEDDFIPFAVLNMMMGGGGSFSAGGPG 355

  Fly   387 KGMYSRLYTKVLNRYHWMYSATAYNHAYGDCGLFCVHGSAPPQHMNDMVEVLTREMMGMAAEPGR 451
            |||:||||..||||:||||:||:|:|:|.|.||.|:|.||.|:.:.:|||::|:|.:.|......
Mouse   356 KGMFSRLYLNVLNRHHWMYNATSYHHSYEDTGLLCIHASADPRQVREMVEIITKEFILMGRTVDL 420

  Fly   452 EELMRSKIQLQSMLLMNLESRPVVFEDVGRQVLVTGQRKRPQHFIKEIESVTAADIQRVAQRLLS 516
            .||.|:|.||.|||:||||||||:|||||||||.|..||.|......|.:|...||:|||.::|.
Mouse   421 VELERAKTQLMSMLMMNLESRPVIFEDVGRQVLATHSRKLPHELCTLIRNVKPEDIKRVASKMLR 485

  Fly   517 SPPSVAARGDIHNLPEMSHITNAVSGSGRTG-LGRRLSLFK 556
            ..|:|||.||:.:||...||..|:  |.|.| |.|...||:
Mouse   486 GKPAVAALGDLTDLPTYEHIQAAL--SSRNGHLPRSYRLFR 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8728	NP_610333.1	PqqL	76..532	CDD:223685	249/464 (54%)
		Peptidase_M16	104..253	CDD:279066	90/148 (61%)
		Peptidase_M16_C	259..461	CDD:282978	101/209 (48%)
Pmpca	NP_775272.1	PqqL	64..503	CDD:223685	246/449 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847176
Domainoid	1	1.000	211	1.000	Domainoid score	I2796
eggNOG	1	0.900	-	-		E1_COG0612
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6078
Inparanoid	1	1.050	520	1.000	Inparanoid score	I1259
Isobase	1	0.950	-	0	Normalized mean entropy	S1277
OMA	1	1.010	-	-		QHG53769
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003938
OrthoInspector	1	1.000	-	-		oto92968
orthoMCL	1	0.900	-	-		OOG6_102381
Panther	1	1.100	-	-	LDO	PTHR11851
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2194
SonicParanoid	1	1.000	-	-		X2236
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.740