DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8728 and Uqcrc2

DIOPT Version :9

Sequence 1:	NP_610333.1	Gene:	CG8728 / 35748	FlyBaseID:	FBgn0033235	Length:	556	Species:	Drosophila melanogaster
Sequence 2:	NP_001006971.1	Gene:	Uqcrc2 / 293448	RGDID:	1359150	Length:	452	Species:	Rattus norvegicus

Alignment Length:	468	Identity:	111/468 - (23%)
Similarity:	199/468 - (42%)	Gaps:	36/468 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 PPLTEPLPNLPEAVYAAPLAESAITKVTTLPNGLRIASEPRYGQFCTVGLVIDSGPRYEVAYPSG 134
            |.|....|.      ..||....: :.|.|||||.|||...|.....:||.|.:|.|||.....|
  Rat    20 PKLKTSAPG------GVPLQPQEL-EFTKLPNGLVIASLENYAPLSRIGLFIKAGSRYENYNYLG 77

  Fly   135 VSHFLEKLAFNSTVNFPNKDAILKELEKNGGICDCQSSRDTLIYAASIDSRAIDSVTRLLADVTL 199
            .||.| :||...|....:...|.:.:|..||.....::|:.:.|........|:.:...|.:||.
  Rat    78 TSHLL-RLASTLTTKGASSFKITRGIEAVGGKLSVTATRENMAYTVEGIRDDIEILMEFLLNVTT 141

  Fly   200 RPTLSDQEVSLARRAVNFELETLGMRPEQEPILMDMIHAAAFRDNTLGLPKLCPLENLDHINRNV 264
            .|.....||:..|..:..:.......|:..  :::.:|..|:: |.|..|..||...:..|....
  Rat   142 APEFRRWEVAALRSQLKIDKAVAFQNPQTR--IIENLHDVAYK-NALANPLYCPDYRMGKITSEE 203

  Fly   265 LMNYLKYHHSPKRMVIAGVGVDHDELVSHVQRYFVEDKAIWETEALEDSGPKQVDTSIAQYTGGL 329
            |..:::.|.:..||.:.|:||.| .::..|...|:..:.     .|..:|.|      |:|.||.
  Rat   204 LHYFVQNHFTSARMALVGLGVSH-SILKEVAEQFLNIRG-----GLGLAGAK------AKYRGGE 256

  Fly   330 VKEQCEIPIYAAAGLPELAHVILGFEGCSHQDKDFVPLCVLNIMMGGGGSFSAGGPGKGMYSRLY 394
            ::||         ....|.|..:..|..:..:.:.....||..::|.|.....|.....:.|:..
  Rat   257 IREQ---------NGDNLVHAAIVAESAAIGNAEANAFSVLQHLLGAGPHIKRGNNTTSLLSQSV 312

  Fly   395 TKVLNRYHWMYSATAYNHAYGDCGLFCVHGSAPPQHMNDMVEVLTREMMGMA-AEPGREELMRSK 458
            .|...:   .:..:|:|.:|.|.|||.::..:......|::.....::..:| ......::..:|
  Rat   313 AKGSQQ---PFDVSAFNASYSDSGLFGIYTVSQAAAAGDVINAAYNQVKAVAQGNLSSADVQAAK 374

  Fly   459 IQLQSMLLMNLESRPVVFEDVGRQVLVTGQRKRPQHFIKEIESVTAADIQRVAQRLLSSPPSVAA 523
            .:|::..||::|:......::|.|.|.||....|...:::|::|..||:.:.|::.:|...|:.|
  Rat   375 NKLKAGYLMSVETSEGFLSEIGSQALATGSYMPPPTVLQQIDAVADADVVKAAKKFVSGKKSMTA 439

  Fly   524 RGDIHNLPEMSHI 536
            .|::.:.|.:..:
  Rat   440 SGNLGHTPFLDEL 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8728	NP_610333.1	PqqL	76..532	CDD:223685	108/456 (24%)
		Peptidase_M16	104..253	CDD:279066	38/148 (26%)
		Peptidase_M16_C	259..461	CDD:282978	40/202 (20%)
Uqcrc2	NP_001006971.1	PqqL	30..435	CDD:223685	104/433 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0612
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810