DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8728 and Uqcrc1

DIOPT Version :9

Sequence 1:	NP_610333.1	Gene:	CG8728 / 35748	FlyBaseID:	FBgn0033235	Length:	556	Species:	Drosophila melanogaster
Sequence 2:	NP_079683.2	Gene:	Uqcrc1 / 22273	MGIID:	107876	Length:	480	Species:	Mus musculus

Alignment Length:	482	Identity:	140/482 - (29%)
Similarity:	221/482 - (45%)	Gaps:	34/482 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 THLPPLTEPLPNL-PEAVYAAPLAESAITKVTTLPNGLRIASEPRYGQFCTVGLVIDSGPRYEVA 130
            |...|....||.| ..|.:|..|.....|:|:.|.||||:|||......||||:.||:|.|||..
Mouse    20 TRRSPALLRLPALRGTATFAQALQSVPETQVSILDNGLRVASEQSSHATCTVGVWIDAGSRYETE 84

  Fly   131 YPSGVSHFLEKLAFNSTVNFPNKDAILKELEKNGGICDCQSSRDTLIYAASIDSRAIDSVTRLLA 195
            ..:|..:|||.|||..|.|.|. :|:.||:|..|...:..|:|:...|.....|:.:..|..|||
Mouse    85 KNNGAGYFLEHLAFKGTKNRPG-NALEKEVESIGAHLNAYSTREHTAYLIKALSKDLPKVVELLA 148

  Fly   196 DVTLRPTLSDQEVSLARRAVNFELETLGMRPEQEPILMDMIHAAAFRDNTLGLPKLCPLENLDHI 260
            |:....:|.|.::...|..:..|::.  .....:.::.|.:||.||:...|......|.||:..:
Mouse   149 DIVQNSSLEDSQIEKERDVILREMQE--NDASMQNVVFDYLHATAFQGTPLAQAVEGPSENVRRL 211

  Fly   261 NRNVLMNYLKYHHSPKRMVIAGV-GVDHDELVSHVQRYFVEDKAIWETEALEDSGPKQVDTSIAQ 324
            :|..|.:||..|:...|||:|.. ||:|.:|:...|::......::|.:|:....|       .:
Mouse   212 SRTDLTDYLNRHYKAPRMVLAAAGGVEHQQLLDLAQKHLSSVSRVYEEDAVPGLTP-------CR 269

  Fly   325 YTGGLVKEQCEIPIYAAAGLPELAHVILGFEGCSHQDKDFVPLCVLNIMMGG-----GGSFSAGG 384
            :||..::.:.:       .|| ||||.:..||....:.|.|.|.|.|.::|.     ||......
Mouse   270 FTGSEIRHRDD-------ALP-LAHVAIAVEGPGWANPDNVTLQVANAIIGHYDCTYGGGVHLSS 326

  Fly   385 PGKGMYSRLYTKVLNRYHWMYSATAYNHAYGDCGLFCVHGSAPPQHMNDMVEVLTREMMGMAAEP 449
            |...:      .|.|:.  ..|...:|.:|.|.||...|.......::|||..|..:.|.:....
Mouse   327 PLASV------AVANKL--CQSFQTFNISYSDTGLLGAHFVCDAMSIDDMVFFLQGQWMRLCTSA 383

  Fly   450 GREELMRSKIQLQSMLLMNLESRPVVFEDVGRQVLVTGQRKRPQHFIKEIESVTAADIQRVAQR- 513
            ...|:.|.|..|::.|:.:|:....|.||:||.:|..|:|.....:...|:.|.|..::.:..:
Mouse   384 TESEVTRGKNILRNALVSHLDGTTPVCEDIGRSLLTYGRRIPLAEWESRIQEVDAQMLRDICSKY 448

  Fly   514 LLSSPPSVAARGDIHNLPEMSHITNAV 540
            .....|:||..|.|..||:.:.|.:.:
Mouse   449 FYDQCPAVAGYGPIEQLPDYNRIRSGM 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8728	NP_610333.1	PqqL	76..532	CDD:223685	136/463 (29%)
		Peptidase_M16	104..253	CDD:279066	48/148 (32%)
		Peptidase_M16_C	259..461	CDD:282978	53/207 (26%)
Uqcrc1	NP_079683.2	PqqL	46..469	CDD:223685	131/448 (29%)
		Peptidase_M16	58..205	CDD:279066	48/149 (32%)
		Peptidase_M16_C	210..395	CDD:282978	53/207 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0612
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810