DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8728 and ucr-1

DIOPT Version :9

Sequence 1:	NP_610333.1	Gene:	CG8728 / 35748	FlyBaseID:	FBgn0033235	Length:	556	Species:	Drosophila melanogaster
Sequence 2:	NP_001343795.1	Gene:	ucr-1 / 175772	WormBaseID:	WBGene00018963	Length:	473	Species:	Caenorhabditis elegans

Alignment Length:	494	Identity:	126/494 - (25%)
Similarity:	208/494 - (42%)	Gaps:	68/494 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 PPLTEPLPNLPEAV------YAAPLAESAITKVTTLPNGLRIASEPRYGQFCTVGLVIDSGPRYE 128
            |.|...:.|...||      .:||.||     ||||.||.|:.:|.......|||:.|::|.|:|
Worm    13 PALNSQVRNASSAVSVKDVLASAPQAE-----VTTLKNGFRVVTEDNGSATATVGVWIETGSRFE 72

  Fly   129 VAYPSGVSHFLEKLAFNSTVNFPNKDAILKELEKNGGICDCQSSRDTLIYAASIDSRAIDSVTRL 193
            ....:||:||||:|....|....:. |:..||...|...:..:.||.........::.::.|..:
Worm    73 NEKNNGVAHFLERLIHKGTGKRASA-ALESELNAIGAKLNSFTERDQTAVFVQAGAQDVEKVVDI 136

  Fly   194 LADVTLRPTLSDQEVSLARRAVNFELETLGMRPEQEPILMDMIHAAAFRDNTLGLPKLCPLENLD 258
            ||||.....|....:...|  ||...|........:.:|.||:|||.|:...|.|..|...|::.
Worm   137 LADVLRNSKLEASTIDTER--VNLLKELEASDDYHQLVLFDMLHAAGFQGTPLALSVLGTSESIP 199

  Fly   259 HINRNVLMNYLKYHHSPKRMVIAGVGVDHDELVSHVQRYFVEDKAIWETEALEDSGPK---QVDT 320
            :|:...|..:.:.|:.|.|||::.||.....:.|...:||.:         |.:..|:   |||.
Worm   200 NISAQQLKEWQEDHYRPVRMVLSAVGGGVSNVSSLADKYFGD---------LSNEYPRKVPQVDG 255

  Fly   321 SIAQYTGGLVKEQCEIPIYAAAGLPELAHVILGFEGCSHQDKDFVPLCVLN--IMMGGGGSFSAG 383
            :  ::||...:       |....:|.: :.....||..:..||.:.|.:.|  |::|......|
Worm   256 T--RFTGSEYR-------YRNDNVPHM-YAAFAVEGVGYAHKDALALQIANQFIVLGQWDVTHA- 309

  Fly   384 GPGKGMYSRLYTKVLNRYHWMYSATAYNHAYGDCGLFCVHGSAPPQHMND---MVEVLTREMMGM 445
             ..:...|||..|: ...|.:::...:|..|.|.|||.::..|....:||   :::.:..|...:
Worm   310 -TSRTAASRLVQKI-GHDHGVHNLQHFNINYKDTGLFGIYFVADAHDLNDTSGIMKSVAHEWKHL 372

  Fly   446 AAEPGREELMRSKIQLQSMLLMNLESRPVVFEDVGRQVLVTGQRKRPQHFIKEIESVTAADIQRV 510
            |:....||:..:|.|.::.|..|||:.........:::|.||..::......:|:.|.|..::..
Worm   373 ASAATEEEVAMAKNQFRTNLYQNLETNTQKAGFNAKELLYTGNLRQLSELEAQIQKVDAGAVREA 437

  Fly   511 AQRLLSSPPSVAARGDIHNLPEMSHITN---AVSGSGRT 546
            ..|                     |:.:   |..|.|||
Worm   438 ISR---------------------HVYDRDLAAVGVGRT 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8728	NP_610333.1	PqqL	76..532	CDD:223685	118/469 (25%)
		Peptidase_M16	104..253	CDD:279066	43/148 (29%)
		Peptidase_M16_C	259..461	CDD:282978	49/209 (23%)
ucr-1	NP_001343795.1	PqqL	30..462	CDD:223685	121/477 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0612
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810