DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment drosha and NFD2

DIOPT Version :9

Sequence 1:	NP_477436.1	Gene:	drosha / 35747	FlyBaseID:	FBgn0026722	Length:	1327	Species:	Drosophila melanogaster
Sequence 2:	NP_173854.1	Gene:	NFD2 / 839061	AraportID:	AT1G24450	Length:	191	Species:	Arabidopsis thaliana

Alignment Length:	214	Identity:	41/214 - (19%)
Similarity:	69/214 - (32%)	Gaps:	84/214 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   739 FHKSLDLLEESIGYRFKNRYLLQLALTHPSYKENYGTNPDHARNSLTNCGIRQPEYGDRKIHYMN 803
            |...|..|:..|||:|.|..||:.|:||.|:.:.
plant    44 FATDLAKLQTQIGYKFNNINLLRRAMTHASFSQE------------------------------- 77

  Fly   804 TRKRGINTLVSIMSRFGKEHETVSNITHNERLEFLGDAVVEFLSSIHLFFMFPELEEGGLATYR- 867
                                       :|:.|...|..::|  :::.|.|:..:::....|..|
plant    78 ---------------------------NNKALSIFGTHIIE--TAVSLQFLAKDIDISSKALGRL 113

  Fly   868 AAIVQN--QHLALLAKKLQLEEFMLYAHGSDLCHELELRHAMANC--FEALMGALLLDGGIKVAD 928
            .:.|.|  ...||...:|.|.:.:..:..:|..:...|      |  |.|:.||:.:|.|
plant   114 ISEVSNVESSCALDGDRLGLGKIIRVSTKTDASNSAIL------CTGFRAIFGAIAIDAG----- 167

  Fly   929 EVFTDALFRQDEKLLSIWK 947
                    ..||.:...||
plant   168 --------TVDEAIKVFWK 178

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
drosha	NP_477436.1	DLL_N	64..136	CDD:289198
		Rnc	738..>974	CDD:223644	41/214 (19%)
		RIBOc	826..942	CDD:197778	25/120 (21%)
		rnc	973..1196	CDD:234633
		RIBOc	990..1117	CDD:197778
		DSRM	1125..1196	CDD:238007
NFD2	NP_173854.1	RIBOc	63..187	CDD:197778	33/195 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003184
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000