DRSC/TRiP Functional Genomics Resources

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Protein Alignment drosha and Mrpl44

DIOPT Version :9

Sequence 1:NP_477436.1 Gene:drosha / 35747 FlyBaseID:FBgn0026722 Length:1327 Species:Drosophila melanogaster
Sequence 2:NP_001026820.1 Gene:Mrpl44 / 301552 RGDID:1309556 Length:332 Species:Rattus norvegicus


Alignment Length:305 Identity:76/305 - (24%)
Similarity:114/305 - (37%) Gaps:68/305 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   934 ALFRQDEKLLSIWKNL--PEHPLQEQE-PLGDRSCIDSYRVLKELTKFEDSIGIKFKHIRLLARA 995
            |.|| .:|.|..|:.|  |..|::..| |..|      |..  |:..|...:...|. :.||..|
  Rat    37 AAFR-FQKELERWRLLRSPPPPVRRSEKPNWD------YHA--EIQAFGSRLQEAFS-LDLLKTA 91

  Fly   996 FTD-----------RSIGFTH----LTLGSNQRLEFLGDTVLQLICSEYLYRHFPE-HHEGHLSL 1044
            |.:           :::|...    |.|..||.|...|.:......:::|...||. ..||    
  Rat    92 FVNSCYIKSEEAKRQNLGIEKEAALLNLKDNQELFEQGLSFSHRCLTQFLEDEFPNLPTEG---- 152

  Fly  1045 LRSSLVNNRT-QAVVC---DDLGMPKYAVYAN---PKADLKTKDRADLLEAFLGALYVDKGLLYC 1102
             ..||||..| :||||   .:|.:.:..:.|.   |:..|:.     ...|.:|||....|....
  Rat   153 -IESLVNFLTGEAVVCHVASNLAVEQLTLSAEFPVPQPVLRR-----TFFAVIGALLQSSGPERA 211

  Fly  1103 EQFCHVCLFPRL---QLFIMNQDWN--DPKSKLQQCCLTLRTMDGGEPDIPYYKVVEASGPTNT- 1161
            ..|....|..::   :||.|   |.  :|..      |.:..:.......|..::...||.|.. 
  Rat   212 ALFIRDFLITQMTGKELFEM---WTIVNPMG------LLVEELKKRNISAPESRLTRQSGSTTAL 267

  Fly  1162 RVYKVAVYFRSKRLATSSGSSIQQAEMNAAKQAL-------ENSR 1199
            .:|.|.:|...:.:|...|.::..||..||:.||       ||.|
  Rat   268 PLYFVGLYCDKRLIAEGPGETVLVAEEEAARVALRKLYGFTENRR 312

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
droshaNP_477436.1 DLL_N 64..136 CDD:289198
Rnc 738..>974 CDD:223644 13/42 (31%)
RIBOc 826..942 CDD:197778 3/7 (43%)
rnc 973..1196 CDD:234633 60/258 (23%)
RIBOc 990..1117 CDD:197778 36/152 (24%)
DSRM 1125..1196 CDD:238007 17/78 (22%)
Mrpl44NP_001026820.1 DSRM 236..304 CDD:294045 17/73 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0571
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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