DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rnh1 and rnaseh1

DIOPT Version :9

Sequence 1:	NP_477315.1	Gene:	rnh1 / 35746	FlyBaseID:	FBgn0023171	Length:	333	Species:	Drosophila melanogaster
Sequence 2:	XP_012818071.1	Gene:	rnaseh1 / 100124876	XenbaseID:	XB-GENE-1011883	Length:	302	Species:	Xenopus tropicalis

Alignment Length:	320	Identity:	116/320 - (36%)
Similarity:	163/320 - (50%)	Gaps:	68/320 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 FYAVASGRRSGVYGSWAECEEQVKGFKNAKYKKFKTRQEADQFVNGCKSYAPQDVAVPLGKEKAS 82
            ||||.:||:.|||.:|.||:|||..|..|:||||.:.::|..||...:|
Frog    32 FYAVRTGRKPGVYNTWDECKEQVDKFPLARYKKFASEEDAWNFVRNQES---------------- 80

  Fly    83 LASWKNSIEVNKNPKYTDEWPEEDHDLAEDDLNAAMNEVEGDPKPSNSSNLPDILNRKRKGTTSG 147
             :|..:|::       |.|..|                     .|:.::.|.:::.::|.
Frog    81 -SSKSSSVD-------TGETKE---------------------PPTQATGLHNVVPQQRA----- 111

  Fly   148 DKRNKIPRHASQVSEAT-------GLKQV-----GAFQFEIDAEGYVIVYTDGSCIGNGRAGACA 200
             ||......:|...||.       .|.::     |||::..|:   |:|||||.|..|||..|.|
Frog   112 -KRPLYKAQSSSTEEAAPKRTKLIDLTELPSSHNGAFKYMGDS---VVVYTDGCCSQNGRLKARA 172

  Fly   201 GYGVYFGKNHQLNAAKPVEGRVTNNVGEIQAAIHAIKTALDLGIQKLCISTDSQFLINSITLWVA 265
            |.|||:|.||.||.|:.:|||.||...|||||..|::.|....|.||.:.|||.|.||.||.|:.
Frog   173 GIGVYWGLNHPLNLAEKLEGRQTNQRAEIQAACRALELAKSQNITKLVLYTDSMFTINGITKWIH 237

  Fly   266 GWKKRDWKLKNNQPVKNVVDFKELDKLLQENNITVKWNYVEAHKGIEGNEMADKLARQGS 325
            .||:..|||...:.|.|..||::||||.|  .:.:||.::..|.|.||||.||:|:|:|:
Frog   238 SWKRNGWKLTTGKKVINREDFEKLDKLTQ--GLDIKWMHIPGHAGFEGNEAADRLSREGA 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rnh1	NP_477315.1	Cauli_VI	19..60	CDD:279957	21/40 (53%)
rnh1	NP_477315.1	RNase_HI_eukaryote_like	183..326	CDD:260012	72/143 (50%)
rnaseh1	XP_012818071.1	Cauli_VI	33..74	CDD:279957	21/40 (53%)
rnaseh1	XP_012818071.1	RNase_HI_eukaryote_like	155..296	CDD:260012	72/143 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	147	1.000	Domainoid score	I4500
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2202
Inparanoid	1	1.050	179	1.000	Inparanoid score	I3909
OMA	1	1.010	-	-		QHG63618
OrthoDB	1	1.010	-	-		D1434144at2759
OrthoFinder	1	1.000	-	-		FOG0003232
OrthoInspector	1	1.000	-	-		oto103134
Panther	1	1.100	-	-	LDO	PTHR10642
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1165
SonicParanoid	1	1.000	-	-		X3158
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	13.110