Protein Alignment MFS12 and TNA1

DIOPT Version :10

• Sequence 1: NP_610332.3
• Gene: MFS12 / 35745
• FlyBaseID: FBgn0033234
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: NP_011776.1
• Gene: TNA1 / 853175
• SGDID: S000003492
• Length: 534
• Species: Saccharomyces cerevisiae
• Alignment Length: 422
• Identity: 96/422 - (22%)
• Similarity: 164/422 - (38%)
• Gaps: 74/422 - (17%)

  Fly    70 FFWGYVVSQVPAGL-LAKRFGAKLVLGLATAIGGILCFFHPIAAKSGW----QSICVLRVLTGLV 129
            ||..||:.. |.|. |.|..|..|::.:.      |..|..|:..:.|    ..:.|:|:|.|..
Yeast   136 FFATYVLFD-PIGTNLLKIMGPPLMMSIC------LTCFGAISLGTAWVKNYAQLIVVRLLLGAF 193

  Fly   130 QGTVYPCVHTLLAKWVPRTERGLLTTGVYSGA----QFGTAVILVTSGFIFESSMGWPGLFYLSG 190
            :|.:||.::..|:....|.:..|....|:|.|    .|| .:|......|..|...|..::.:.|
Yeast   194 EGMIYPAINMYLSVCYRREQYALRFAFVFSAACLSSSFG-GLIAYGCSKISGSLKDWQYIYIVEG 257

  Fly   191 GLSLAWALLFFWQAANEPVTASRISKGEVEYI-ESLTGSNSSSQSMPVPWMSIFR---------- 244
            .:||.:...:.:..:.....:...:|.|.||| |.....|:........|..:::
Yeast   258 CISLGFVPFYAFGLSKNLEDSWFFNKEEKEYISERYKTMNTFDPDEKFEWFQVWQAVKDVKTWAS 322

  Fly   245 SPAFYGLLAAHCGFTWGFYTLLTEMPTYMSMVLQLNVKSNAFLSSLP-YFAMGLLCFVVSPISDL 308
            :.|.:|:...    |:|....|..:.|.|...   ||:  |.|.::| ||...::.|:.:..||.
Yeast   323 AVALFGIDLT----TFGLTVFLPIIITSMGFT---NVR--AQLMTVPIYFLTAIVFFICAVWSDR 378

  Fly   309 LINRGTISITTARKLFNSIGQWGPMACLIGLGYMTADEKTWAILLLTLAVGINAGCSCGYLINHI 373
            :..|....:...  |..|||      ..|.||......:.:.:.:|.:.:.:||.|:|.:|..:
Yeast   379 IKLRSPFILGAC--LTTSIG------IAIVLGSQVHGVRYFGVYILCMGIYVNAACNCLWLSGN- 434

  Fly   374 DLSPNF--AGPMMGVTNGIAGVTSIIAPLVVGAIVSDEEDPSQWRMVFFITGGIYLVCNTIFVIF 436
              :.|:  ....:|: |...|..|   .||.|.|...::.|.      :|.|....:...:|.||
Yeast   435 --TGNYFKRATALGI-NLFFGSGS---GLVSGQIFVAKDKPR------YIKGLSISLAFQVFSIF 487

  Fly   437 GKATIQIWNEPPSTSSTMTLRSHQENDSKSIV 468
             ...:||:            ...:|||.|..:
Yeast   488 -MTVVQIF------------LYKRENDKKKAI 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS12	NP_610332.3	MFS_SLC17	22..437	CDD:340876	89/389 (23%)
TNA1	NP_011776.1	MFS_FEN2_like	87..490	CDD:340885	90/392 (23%)