Protein Alignment MFS12 and SLC17A7

DIOPT Version :9

• Sequence 1: NP_610332.3
• Gene: MFS12 / 35745
• FlyBaseID: FBgn0033234
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: NP_064705.1
• Gene: SLC17A7 / 57030
• HGNCID: 16704
• Length: 560
• Species: Homo sapiens
• Alignment Length: 451
• Identity: 136/451 - (30%)
• Similarity: 220/451 - (48%)
• Gaps: 17/451 - (3%)

  Fly    14 GLGVRHWQAVLLFVGMMINYFQRVNISAAIVPMTQSTA---GAPF------YTWDTSDKSLILSS 69
            ||..|:..|::..:|..|::..|.|:..|||.|..::.   |...      ::||.....||..|
Human    58 GLPRRYIIAIMSGLGFCISFGIRCNLGVAIVSMVNNSTTHRGGHVVVQKAQFSWDPETVGLIHGS 122

  Fly    70 FFWGYVVSQVPAGLLAKRFGAKLVLGLATAIGGILCFFHPIAAKSGWQSICVLRVLTGLVQGTVY 134
            |||||:|:|:|.|.:.::|.|..|.|.|......|....|.||:..:..:..:|:|.|||:|..|
Human   123 FFWGYIVTQIPGGFICQKFAANRVFGFAIVATSTLNMLIPSAARVHYGCVIFVRILQGLVEGVTY 187

  Fly   135 PCVHTLLAKWVPRTERGLLTTGVYSGAQFGTAVILVTSGFIFESSMGWPGLFYLSGGLSLAWALL 199
            |..|.:.:||.|..||..|.|..:.|:..|..|.:..:|.:.:.| ||..:||:.|...:.|.|.
Human   188 PACHGIWSKWAPPLERSRLATTAFCGSYAGAVVAMPLAGVLVQYS-GWSSVFYVYGSFGIFWYLF 251

  Fly   200 FFWQAANEPVTASRISKGEVEYIESLTGSNSSSQS----MPVPWMSIFRSPAFYGLLAAHCGFTW 260
            :...:...|.....||:.|.:|||...|.::...:    ...||...|.|...|.::.|:...:|
Human   252 WLLVSYESPALHPSISEEERKYIEDAIGESAKLMNPLTKFSTPWRRFFTSMPVYAIIVANFCRSW 316

  Fly   261 GFYTLLTEMPTYMSMVLQLNVKSNAFLSSLPYFAMGLLCFVVSPISDLLINRGTISITTARKLFN 325
            .||.||...|.|...|....:.....:|:||:..|.::..:...|:|.|.:|..:|.|..|||.|
Human   317 TFYLLLISQPAYFEEVFGFEISKVGLVSALPHLVMTIIVPIGGQIADFLRSRRIMSTTNVRKLMN 381

  Fly   326 SIGQWGPMACLIGLGYMTADEKTWAILLLTLAVGINAGCSCGYLINHIDLSPNFAGPMMGVTNGI 390
            ..|.......|:.:||  :..|..||..|.||||.:.....|:.:||:|::|.:|..:||::||:
Human   382 CGGFGMEATLLLVVGY--SHSKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGV 444

  Fly   391 AGVTSIIAPLVVGAIVSDEEDPSQWRMVFFITGGIYLVCNTIFVIFGKATIQIWNEPPSTS 451
            ..::.::.|::||| ::..:...:|:.||.|...::......:.:|.....|.|.||...|
Human   445 GTLSGMVCPIIVGA-MTKHKTREEWQYVFLIASLVHYGGVIFYGVFASGEKQPWAEPEEMS 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS12	NP_610332.3	MFS	23..436	CDD:119392	126/425 (30%)
		2A0114euk	25..447	CDD:129972	129/434 (30%)
SLC17A7	NP_064705.1	MFS_SLC17A6_7_8_VGluT	66..490	CDD:340940	127/427 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	497..560		4/8 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148573
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.750