Protein Alignment MFS12 and slc17a8

DIOPT Version :10

• Sequence 1: NP_610332.3
• Gene: MFS12 / 35745
• FlyBaseID: FBgn0033234
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: NP_001076304.1
• Gene: slc17a8 / 563467
• ZFINID: ZDB-GENE-060503-416
• Length: 590
• Species: Danio rerio
• Alignment Length: 477
• Identity: 141/477 - (29%)
• Similarity: 233/477 - (48%)
• Gaps: 21/477 - (4%)

  Fly    14 GLGVRHWQAVLLFVGMMINYFQRVNISAAIVPMTQSTA----GAPF-----YTWDTSDKSLILSS 69
            ||..|:..|:|..:|..|::..|.|:..|||.|..:..    |...     :.||.....||..|
Zfish    71 GLPKRYIIAMLSGLGFCISFGIRCNLGVAIVEMVNNNTVYINGTAVMQPAQFNWDPETVGLIHGS 135

  Fly    70 FFWGYVVSQVPAGLLAKRFGAKLVLGLATAIGGILCFFHPIAAKSGWQSICVLRVLTGLVQGTVY 134
            |||||:|:|:|.|.::.:..|..|.|.|..:..:|..|.|.||:..:..:..:|:|.|||:|..|
Zfish   136 FFWGYIVTQIPGGFISNKLAANRVFGAAIFLTSVLNMFIPSAARVHYGCVMFVRILQGLVEGVTY 200

  Fly   135 PCVHTLLAKWVPRTERGLLTTGVYSGAQFGTAVILVTSGFIFESSMGWPGLFYLSGGLSLAWALL 199
            |..|.:.:||.|..||..|.|..:.|:..|..:.:..:|.:.: .:|||.:||:.|...:.|.:.
Zfish   201 PACHGMWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQ-YVGWPSVFYIYGVFGIIWYIF 264

  Fly   200 FFWQAANEPVTASRISKGEVEYIESLTGSN----SSSQSMPVPWMSIFRSPAFYGLLAAHCGFTW 260
            :...|.|.|.....||:.|..|||:..|..    ||::....||...|.|...|.::.|:...:|
Zfish   265 WILLAYNSPAVHPTISEEERNYIETSIGEGANLMSSTEKFKTPWREFFTSMPVYAIIVANFCRSW 329

  Fly   261 GFYTLLTEMPTYMSMVLQLNVKSNAFLSSLPYFAMGLLCFVVSPISDLLINRGTISITTARKLFN 325
            .||.||...|.|...|....:.....||::|:..|.::..:...::|.|.:|..:|.||.||:.|
Zfish   330 TFYLLLISQPAYFEEVFGFPISKVGILSAVPHMVMTIIVPIGGQLADFLRSRKILSTTTVRKIMN 394

  Fly   326 --SIGQWGPMACLIGLGYMTADEKTWAILLLTLAVGINAGCSCGYLINHIDLSPNFAGPMMGVTN 388
              ..|....:..::|..:..|    .||..|.||||.:.....|:.:||:|::|.:|..:||::|
Zfish   395 CGGFGMEATLLLVVGFSHTRA----VAISFLILAVGFSGFAISGFNVNHLDIAPRYASILMGISN 455

  Fly   389 GIAGVTSIIAPLVVGAIVSDEEDPSQWRMVFFITGGIYLVCNTIFVIFGKATIQIWNEPPSTSST 453
            |:..::.::.||:|||: :..:...:|:.||.|...::......:.||.....|.|.:|.:||..
Zfish   456 GVGTLSGMVCPLIVGAL-TKHKTRLEWQHVFVIASMVHYTGVIFYAIFASGEKQDWADPENTSDE 519

  Fly   454 MTLRSHQENDSKSIVPTSDKDI 475
            ......::..:....|:||..:
Zfish   520 KCGIIGEDELADETEPSSDSGL 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS12	NP_610332.3	MFS_SLC17	22..437	CDD:340876	129/429 (30%)
slc17a8	NP_001076304.1	MFS_SLC17A6_7_8_VGluT	79..503	CDD:340940	129/429 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	526..590		3/16 (19%)