Protein Alignment MFS12 and SLC37A1

DIOPT Version :9

• Sequence 1: NP_610332.3
• Gene: MFS12 / 35745
• FlyBaseID: FBgn0033234
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: XP_011527916.1
• Gene: SLC37A1 / 54020
• HGNCID: 11024
• Length: 577
• Species: Homo sapiens
• Alignment Length: 541
• Identity: 122/541 - (22%)
• Similarity: 194/541 - (35%)
• Gaps: 159/541 - (29%)

  Fly     2 GFEPSEDKARPGGL------GVRHWQAVLLFVGMMINYF-------------------------- 34
            |:.|.|..|.|..|      ...|.....:|:...:.|.
Human    26 GWSPGEGTAAPSSLPHTSPCASLHLYRAFIFILTFLLYASFHLSRKPISIVKGELHKYCTAWDEA 90

  Fly    35 -------QRVNISAA--IVPMTQSTAG-APFYTWDTSDKSLILS----SFFWGYVVSQVPAGLLA 85
                   .|.:.|||  .:|..::..| |||   |.::...:|.    ||...|.|....:|::.
Human    91 DVRFSSQNRKSGSAAPHQLPDNETDCGWAPF---DKNNYQQLLGALDYSFLCAYAVGMYLSGIIG 152

  Fly    86 KR--------FGAKLVLGLATAIGGILCFFHPIAAKSGWQSICVLRVLTGLVQGTVYPCVHTLLA 142
            :|        || .|..|..||:.| |.:|:.|   ..:....|.:|:.||||.|.:|.|.|.|.
Human   153 ERLPIRYYLTFG-MLASGAFTALFG-LGYFYNI---HSFGFYVVTQVINGLVQTTGWPSVVTCLG 212

  Fly   143 KWVPRTERGLLTTGVY-SGAQFGTAVILVTSGFIFESSMGWPGLFYLSGGLSLAWALLFFWQAAN 206
            .|..:..|||: .||: |....|..:..:.:|:..  |..|...|.:.|.:..|..::.|.....
Human   213 NWFGKGRRGLI-MGVWNSHTSVGNILGSLIAGYWV--STCWGLSFVVPGAIVAAMGIVCFLFLIE 274

  Fly   207 EP---------VTASR----------------------------------ISKGEV--EYIESLT 226
            .|         ||.|:                                  ..||.:  .::..|.
Human   275 HPNDVRCSSTLVTHSKGYENGTNRLRLQKQILKSEKNKPLDPEMQCLLLSDGKGSIHPNHVVILP 339

  Fly   227 GSNSS-------SQSMPVPWMSIFRSPAFYGLLAAHCGFTWGFYTLLTEMPTYMSMVLQLNVKSN 284
            |...|       :.::.:|.:..|.....:..|.:        ||.|..:|.|::.|..|:.|..
Human   340 GDGGSGTAAISFTGALKIPGVIEFSLCLLFAKLVS--------YTFLFWLPLYITNVDHLDAKKA 396

  Fly   285 AFLSSLPYFAMGLLC--FVVSPISDLLINR----GTISITTARKL--FNSIGQWG---PMACLIG 338
            ..||:|  |.:|.:.  .:...|||.|..|    |.:.:..|..|  |:::.:.|   .:|.|:.
Human   397 GELSTL--FDVGGIFGGILAGVISDRLEKRASTCGLMLLLAAPTLYIFSTVSKMGLEATIAMLLL 459

  Fly   339 LGYMTADEKTWAILLLTLAVGINAGCSCGYLINHIDLSPNFAGPMMGVT---NGIAGVTSIIAPL 400
            .|.:.:...|    |:|.||..:.|       .|..|..| |..:..||   :|...|.:.:.||
Human   460 SGALVSGPYT----LITTAVSADLG-------THKSLKGN-AHALSTVTAIIDGTGSVGAALGPL 512

  Fly   401 VVGAIVSDEEDPSQWRMVFFI 421
            :.|.:     .||.|..||::
Human   513 LAGLL-----SPSGWSNVFYM 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS12	NP_610332.3	MFS	23..436	CDD:119392	115/514 (22%)
		2A0114euk	25..447	CDD:129972	115/512 (22%)
SLC37A1	XP_011527916.1	UhpC	51..543	CDD:225180	115/516 (22%)
		MFS	129..489	CDD:119392	90/389 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148669
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930