DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS12 and MFS9

DIOPT Version :9

Sequence 1:	NP_610332.3	Gene:	MFS12 / 35745	FlyBaseID:	FBgn0033234	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_650889.1	Gene:	MFS9 / 42426	FlyBaseID:	FBgn0038799	Length:	502	Species:	Drosophila melanogaster

Alignment Length:	466	Identity:	149/466 - (31%)
Similarity:	243/466 - (52%)	Gaps:	31/466 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 RHWQ------AVLLFVGMMINYFQRVNISAAIVPMTQSTA-----GAPFY----TWDTSDKSLIL 67
            |.|:      .:|.|.|....|..|||:|.|||.||::..     |...|    .||:..|.|||
  Fly    32 RFWRKQRYIVVLLAFFGFFNVYSLRVNLSVAIVAMTENRTVFDADGNVSYQQDFPWDSKQKGLIL 96

  Fly    68 SSFFWGYVVSQVPAGLLAKRFGAKLVLGLATAIGGILCFFHPIAAKSGWQSICVLRVLTGLVQGT 132
            ||||:||:::|...|.:..:.|..:|.|.......||....|:||....:....:|::.|..:|.
  Fly    97 SSFFYGYILTQFLGGYIGTKIGGNIVFGTGIGSTAILTLLTPMAASHSLEMFLFVRIIEGFFEGV 161

  Fly   133 VYPCVHTLLAKWVPRTERGLLTTGVYSGAQFGTAVILVTSGFIFESSMGWPGLFYLSGGLSLAWA 197
            .:|.:|.:.|:|.|..||..:.:..::|...||.|.:..|||: .:..||..:||:.|.:.:.|.
  Fly   162 TFPGIHAVWARWSPPLERSRMASIAFAGNYAGTVVAMPCSGFL-ATKYGWESVFYVFGTIGVIWY 225

  Fly   198 L--LFFWQAANEPVTASRISKGEVEYIESLTGSNSSSQSMPVPWMSIFRSPAFYGLLAAHCGFTW 260
            :  |.|.:|.  |......||.|.:||:...| ...|:.:..||.:||.|..||.::|:|....|
  Fly   226 ITWLVFVKAG--PELDRFCSKEECDYIQKTIG-YVGSKHVKHPWRAIFTSMPFYAIMASHFSENW 287

  Fly   261 GFYTLLTEMPTYMSMVLQLNVKSNAFLSSLPYFAMGLLCFVVSPISDLLINRGTISITTARKLFN 325
            |||||||::|:::...|..::.....||::||.|||:|..|...::|.|..:|..:.|..|:.||
  Fly   288 GFYTLLTQLPSFLRDTLNFDLGKTGILSAVPYLAMGILLAVSGYLADWLQVKGIWTTTQVRRNFN 352

  Fly   326 SIGQWGPMACLIGLGYMTADEKTWAILLLTLAVGINAGCSCGYLINHIDLSPNFAGPMMGVTNGI 390
            ..........::...|:.  :.||:::.||:|||:.|....|:.:||:|::|..|..:||:.|..
  Fly   353 CGAFLAQTVFMMLTAYLL--DPTWSVVSLTIAVGLGAFAWSGFAVNHLDIAPQHASVLMGIGNTF 415

  Fly   391 AGVTSIIAPLVVGAIVSDEEDPSQWRMVFFITGGIYLVCNTIFVIFGKATIQIWNEPPSTSSTMT 455
            |.:..|::||:.|.:|:::.. .:||::|||:.|||||...|:..:....:|.|.:.|...:
  Fly   416 ATIPGIVSPLLTGYVVTNQTS-DEWRIIFFISAGIYLVGCVIYWFYCSGDLQEWAKTPEQKA--- 476

  Fly   456 LRSHQENDSKS 466
                ||.:.|:
  Fly   477 ----QEAEEKA 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS12	NP_610332.3	MFS	23..436	CDD:119392	141/423 (33%)
MFS12	NP_610332.3	2A0114euk	25..447	CDD:129972	142/432 (33%)
MFS9	NP_650889.1	2A0114euk	38..477	CDD:129972	144/452 (32%)
MFS9	NP_650889.1	MFS	42..460	CDD:119392	141/424 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.970