DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS12 and CG9254

DIOPT Version :9

Sequence 1:	NP_610332.3	Gene:	MFS12 / 35745	FlyBaseID:	FBgn0033234	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_609664.1	Gene:	CG9254 / 34773	FlyBaseID:	FBgn0028513	Length:	481	Species:	Drosophila melanogaster

Alignment Length:	456	Identity:	138/456 - (30%)
Similarity:	230/456 - (50%)	Gaps:	43/456 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 AVLLFVGMMINYFQRVNISAAIV------------------PMTQSTAGAPF----YTWDTSDKS 64
            |::.|..:...|..|:.:|.||.                  |..||...:.|    |.|....:.
  Fly    27 AIMGFFAIFNAYTMRICLSQAITVLVVKRNYTIFHTEAICEPDDQSDPSSTFEGGDYDWSQEKQG 91

  Fly    65 LILSSFFWGYVVSQVPAGLLAKRFGAKLVLGLATAIGGILCFFHPIA-AKSGWQSICVLRVLTGL 128
            |||:||:.||:|:.:|.|:||.:||.|..|.|......|.....|:. ...|..::.|||||.||
  Fly    92 LILASFYIGYIVTHLPGGILADKFGGKWTLSLGIFFTAIFTLLTPVCIVYGGADALIVLRVLMGL 156

  Fly   129 VQGTVYPCVHTLLAKWVPRTERGLLTTGVYSGAQFGTAVILVTSGFIFESSMGWPGLFYLSGGLS 193
            .:||.:|.:..|||.|||..|||:|...|..|.|.|:....:.||::. |||.||.:||:...::
  Fly   157 GEGTTFPALSVLLASWVPANERGMLGALVLGGGQMGSIAGNIISGYVL-SSMDWPWVFYVFAIIA 220

  Fly   194 LAWALLFFWQAANEPVTASRISKGEVEYIESLTGSNSSSQSMP--------VPWMSIFRSPAFYG 250
            |.|.::|.....:.|.|...|...|..::         :|.:|        .|:.:|..|...:.
  Fly   221 LVWFVVFTLVCFSSPFTHPYIKPEERAFL---------AQEVPPPDKNKPKTPFFAILTSIPMWA 276

  Fly   251 LLAAHCGFTWGFYTLLTEMPTYMSMVLQLNVKSNAFLSSLPYFAMGLLCFVVSPISDLLINRGTI 315
            |::|..|..||||.:::.:|.|||.||:.::|||...|||||..|.::..:...::|.:|.|..:
  Fly   277 LISAQIGHDWGFYIMVSYLPKYMSDVLRFSIKSNGLYSSLPYVTMWIMSLLSGCVADQMIKRNCM 341

  Fly   316 SITTARKLFNSIGQWGPMACLIGLGYMTADEKTWAILLLTLAVGINAGCSCGYLINHIDLSPNFA 380
            |.|..||:...:..:||...::...|...: :...:.|.|:.:|:......|..:..:|:|||:|
  Fly   342 STTNTRKIMTGVAAFGPAVFMVAASYAGCN-RGMVVALFTITMGLMGTYYAGMKLTPLDMSPNYA 405

  Fly   381 GPMMGVTNGIAGVTSIIAPLVVGAIVSDEEDPSQWRMVFFITGGIYLVCNTIFVIFGKATIQIWN 445
            |.:|.:||||..:|.:::|.:|| :::......:||:||::..|:.:|...::.|:....:|.:|
  Fly   406 GTLMAITNGIGAITGVVSPYLVG-VMTPNATLLEWRLVFWVAFGVLVVTAIVYCIWASGDVQPFN 469

  Fly   446 E 446
            :
  Fly   470 D 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS12	NP_610332.3	MFS	23..436	CDD:119392	134/443 (30%)
MFS12	NP_610332.3	2A0114euk	25..447	CDD:129972	137/453 (30%)
CG9254	NP_609664.1	2A0114euk	28..466	CDD:129972	135/449 (30%)
CG9254	NP_609664.1	MFS	82..461	CDD:119392	125/390 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451930
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	9	8.890