DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS12 and SPCC757.13

DIOPT Version :9

Sequence 1:	NP_610332.3	Gene:	MFS12 / 35745	FlyBaseID:	FBgn0033234	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_587688.1	Gene:	SPCC757.13 / 2539039	PomBaseID:	SPCC757.13	Length:	522	Species:	Schizosaccharomyces pombe

Alignment Length:	490	Identity:	106/490 - (21%)
Similarity:	183/490 - (37%)	Gaps:	106/490 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 LLFVGMMINYFQRVNIS-AAIVPMTQSTAGAPFYTWDTSDKSLILSSFFWGYVVSQVPAGLLAKR 87
            ::.:..||.|..:..:| ||:..|...|      ..|....|.:.:.|:.||:|:|.||.:|.::
pombe    80 VMCITYMIQYLDKTALSYAALYGMKTDT------HIDGHTYSSMTTLFYAGYLVAQYPAAILMQK 138

  Fly    88 FGAKLVLGLATAI-GGILCFFHPIAAKSGWQSICVLRVLTGLVQGTVYPCVHTLLAKWVPRTERG 151
            ......:.....: ..::|.   :||.....|:..||.|.|:.:.::.|....:.|.|..|.|:.
pombe   139 CRLSYFIFCNVFLWSAMVCL---MAACRNGPSLLGLRFLAGIFEASITPAFINITAMWYRREEQP 200

  Fly   152 LLTTGVYSG---AQFGTAVILVTSGFIFESSMGWPGLFYLSGGLSLAWALLFFWQAANEPVTASR 213
            :.|...|:.   ||...:::....|.|......|..:|.:.|.:||.|.::|.:..:| |..|..
pombe   201 MRTLCWYAFNGIAQIIGSILSYGLGHIHGKVASWRYVFIVIGLMSLGWGVVFVFIPSN-PSKARF 264

  Fly   214 ISKGEVEY-IESLTGSNSSSQSMPVPWMSIFRSPAFYG-------LLAAHCGFTWG---FYTLLT 267
            :|..|... :|.:..:.:..::....|...:.  ||..       |....|..|.|   |.||:.
pombe   265 LSSREKRIALERVRDNRTGLENKQFKWKHAYE--AFLDPQVIMITLFTGVCMITNGIGVFSTLII 327

  Fly   268 EMPTYMSM-VLQLNVKSNAFLSSLPYFAMGLLC-------FVVSPISDLLINRGTISITTARKLF 324
            :...|..: ...||:...| :.....|..|:||       .::....:.|...|.:.|.   |:.
pombe   328 KGLGYNELHSAVLNMPLGA-IEVAAMFISGVLCKVFKNGRLLIGVFMNCLTLAGCLMIW---KIP 388

  Fly   325 NS------IGQWGPM------ACLIGL------GYMTADEKTWAILLLTLAVGINAGCSCGYLIN 371
            :|      :|.|..|      |.|:.|      || |....|.|.:.:..:||
pombe   389 DSNPYGRLVGVWFTMWVPASSALLLSLISSNVAGY-TKKTVTSATVFVFYSVG------------ 440

  Fly   372 HIDLSPNFAGPMM---GVT-NGIAGVTSIIAPLVVGAIVSDEEDPSQWRMVFFITGGIYLVCNTI 432
                  |...|.:   |.| ..|.|:.::|..|.:  |::          :.|:..|.|:..|
pombe   441 ------NIVSPQLFKSGQTPEYIEGIQAMIVSLCI--IIA----------IAFVLTGYYIYEN-- 485

  Fly   433 FVIFGKATIQIWNEPPSTSST------MTLRSHQE 461
                 |...::..|.||...:      |.|...|:
pombe   486 -----KRRDRLLAEDPSLGESIKNEEFMDLTDRQQ 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS12	NP_610332.3	MFS	23..436	CDD:119392	99/457 (22%)
MFS12	NP_610332.3	2A0114euk	25..447	CDD:129972	100/467 (21%)
SPCC757.13	NP_587688.1	MFS	80..477	CDD:119392	96/443 (22%)
SPCC757.13	NP_587688.1	2A0114	83..478	CDD:273326	96/441 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
TreeFam	0	0.000	Not matched by this tool.
	4	4.050