Protein Alignment MFS12 and cima-1

DIOPT Version :9

• Sequence 1: NP_610332.3
• Gene: MFS12 / 35745
• FlyBaseID: FBgn0033234
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: NP_001294208.1
• Gene: cima-1 / 24104589
• WormBaseID: WBGene00018473
• Length: 543
• Species: Caenorhabditis elegans
• Alignment Length: 458
• Identity: 109/458 - (23%)
• Similarity: 202/458 - (44%)
• Gaps: 36/458 - (7%)

  Fly    38 NISAAIVPMTQSTAGAPFY------TWDTSDKSLILSSFFWGYVVSQVPAGLLAKRFGAKLVLGL 96
            |::.|::.||    ..|.:      .|.:..:.|:|::...|.:: .:..|:.|.|...|.::
 Worm    87 NLAVALICMT----SCPVHGYGGTLEWQSQQEGLVLAAQNAGSLI-MIVTGMWADRLNGKWMV-- 144

  Fly    97 ATAIGGILC-----FFHPIAAKSGWQSICVLRVLTGLVQGTVYPCVHTLLAKWVPRTERGLLTTG 156
              .||.:||     ....:|:||.|.:: :.|:..|.....:.|.|::|:.:|.|:.||......
 Worm   145 --FIGLLLCCIGNLMLPLLASKSFWFAV-LARISIGASDACLMPAVNSLITRWFPQAERPAAIGL 206

  Fly   157 VYSGAQFGTAVILVTSGFIF---ESSMGWPGLFYLSGGLSLAWALLFFWQAANEPVTASRISKGE 218
            :..|.|.||..||.|:|::.   :...|||.:||||..:|:...:.:....|::|.....||..|
 Worm   207 ISGGRQIGTLFILPTAGYLCTRKDILDGWPAIFYLSATISVLVTVFWIPFGADKPAKQICISSRE 271

  Fly   219 VEYIESLTGSNS----SSQSMPVPWMSIFRSPAFYGLLAAHCGFTWGFYTLLTEMPTYMSMVLQL 279
            .|:||:.....|    :.::..||:.::..|...:..:.|.....:....:|..:|.||..||:.
 Worm   272 KEFIETRIACESIGKRTDRTRRVPYGAMLHSKPLWACIFALICHEYPLVIMLQFLPNYMRDVLEF 336

  Fly   280 NVKSNAFLSSLPYFAMGLLCFVVSPISDLLINRGTISITTARKLFNSIGQWGPMACLIGLGYMTA 344
            ....|..:::||...:.|.....|.:|..|..:..:..|...|.||::...|...|:..:.:...
 Worm   337 APTKNGIIAALPILCLFLSKTFSSSLSSYLTTKLRLDKTFVCKGFNAVASAGLAICISFVPFFNK 401

  Fly   345 DEKTWAILLLTLAVGINAGC-SCGYLINHIDLSPNFAGPMMGVTNGIAGVTSIIAPLVVGAIVSD 408
            :....|:..|..|: |.||. :.|.:...:.::|.|:|.:.|.:.......||...::...|| .
 Worm   402 ESAFLAVFCLCGAM-IFAGLHTPGVITAMVQIAPAFSGIITGWSFFAVAWFSIGNKILTKYIV-Q 464

  Fly   409 EEDPSQWRMVFFITGGIYLVCNTIFVIFGKATIQIWNEPPSTSSTM-----TLRSHQENDSKSIV 468
            ....::|.|||.::..:..:...:|.|:|.|..:.|..|.|..|..     ::|......|::..
 Worm   465 SGSVTEWGMVFRVSALVAALPVIVFTIWGSADREWWAAPSSKCSVASFHRPSIRDRSREMSRATS 529

  Fly   469 PTS 471
            .||
 Worm   530 STS 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS12	NP_610332.3	MFS	23..436	CDD:119392	98/416 (24%)
		2A0114euk	25..447	CDD:129972	102/427 (24%)
cima-1	NP_001294208.1	2A0114euk	63..506	CDD:129972	103/430 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	42	1.000	Domainoid score	I8440
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.920