Protein Alignment MFS12 and Slc17a2

DIOPT Version :10

• Sequence 1: NP_610332.3
• Gene: MFS12 / 35745
• FlyBaseID: FBgn0033234
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: XP_006516709.1
• Gene: Slc17a2 / 218103
• MGIID: 2443098
• Length: 480
• Species: Mus musculus
• Alignment Length: 480
• Identity: 144/480 - (30%)
• Similarity: 231/480 - (48%)
• Gaps: 45/480 - (9%)

  Fly     1 MGFEPSEDKARPGGLGVRHWQAVLLFVGMMINYFQRVNISAAIVPMTQST--------------- 50
            |..:|:..|. .|...:|:..|:::.........|||::|.||:.|..||
Mouse     1 MDEKPTTRKG-SGFCSLRYALALIMHFSNFTMITQRVSLSIAIIAMVNSTQHQDPANASTEGPVM 64

  Fly    51 --------------AGAPFYTWDTSDKSLILSSFFWGYVVSQVPAGLLAKRFGAKLVLGLATAIG 101
                          ..|..|.|.|..:.:|.||..:|.:::.:|:|.||..||||.:||....|.
Mouse    65 DLLSNQSRGIKDFSTRAAVYQWSTETQGIIFSSISYGIILTLIPSGYLAGIFGAKQILGAGLLIS 129

  Fly   102 GILCFFHPIAAKSGWQSICVLRVLTGLVQGTVYPCVHTLLAKWVPRTERGLLTTGVYSGAQFGTA 166
            .:|..|.|:||..|...:.|:|.:.|:.||..:....|:.|||.|..||..||:...||...|:.
Mouse   130 SLLTLFTPLAADFGVILVIVIRTVQGMAQGMAWTGQFTIWAKWAPPLERSKLTSIAGSGEDVGSV 194

  Fly   167 VIL--VTSGFIFESSMGWPGL-FYLSGGLSL----AWALLFFWQAANEPVTASRISKGEVEYIES 224
            .:|  ...|.|   ::...|| |||   |.|    ...:|:|....::|:....||..|.|:|.|
Mouse   195 WVLHHPLCGRI---NLTGTGLAFYL---LHLCIGCVCCVLWFTVIYDDPMHHPCISVREKEHITS 253

  Fly   225 LTGSNSSSQSMPVPWMSIFRSPAFYGLLAAHCGFTWGFYTLLTEMPTYMSMVLQLNVKSNAFLSS 289
            .....|||....||..::.|....:.:........|....::|.:|||:|.||.:|::.:..|||
Mouse   254 SVAQQSSSPRRSVPIKAMVRCLPLWAIFMGFFSHFWLCTIIITYLPTYISTVLHVNIRDSGVLSS 318

  Fly   290 LPYFAMGLLCFVVSPISDLLINRGTISITTARKLFNSIGQWGPMACLIGLGYMTADEKTWAILLL 354
            ||:.|......:...::|.|::|..:|:.|.||||:|:|...|..|.:.|.::|:.... .|:||
Mouse   319 LPFIAASSCTILGGQMADFLLSRNLLSLITVRKLFSSLGLLLPSLCAVALPFVTSSYIA-TIVLL 382

  Fly   355 TLAVGINAGCSCGYLINHIDLSPNFAGPMMGVTNGIAGVTSIIAPLVVGAIVSDEEDPSQWRMVF 419
            .|..|.:..|..|::||.:|::|.:|..:||::.|......||:....|.::|.:.: |.||.||
Mouse   383 ILIPGTSNLCDSGFIINTLDVAPRYASFLMGISRGFGLTAGIISSTTTGFLISQDSE-SGWRNVF 446

  Fly   420 FITGGIYLVCNTIFVIFGKATIQIW 444
            |::..:.:.....::|||:|.||.|
Mouse   447 FLSAAVNMFGLIFYLIFGQAEIQSW 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS12	NP_610332.3	MFS_SLC17	22..437	CDD:340876	133/450 (30%)
Slc17a2	XP_006516709.1	MFS_SLC17	21..464	CDD:340876	133/450 (30%)