Protein Alignment MFS12 and slc-17.4

DIOPT Version :10

• Sequence 1: NP_610332.3
• Gene: MFS12 / 35745
• FlyBaseID: FBgn0033234
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: NP_503071.2
• Gene: slc-17.4 / 189054
• WormBaseID: WBGene00012130
• Length: 573
• Species: Caenorhabditis elegans
• Alignment Length: 512
• Identity: 126/512 - (24%)
• Similarity: 218/512 - (42%)
• Gaps: 70/512 - (13%)

  Fly    23 VLLFVGMMINYFQRVNISAAIVPMTQSTA----GAPF---------------------------- 55
            :|...|.....|.|::|:.::..|..|||    .|.|
 Worm    35 LLCMAGFCCTTFMRMHIAISMTCMINSTALALESAVFPEAFENSSSIFEELEPVSNGACSSNADV 99

  Fly    56 -----------YTWDTSDKSLILSSFFWGYVVSQVPAGLLAKRFGAKLVLGLATAIGGILCFFHP 109
                       ..|::.:::||.|..|||.:::.:|:.....|:..:.||..|.....::....|
 Worm   100 NKKVVVDYGGQLVWNSQEQNLIFSGTFWGSIITVLPSMFFINRYSPRYVLQAAVGCYILMTAITP 164

  Fly   110 -IAAKSGWQSICVLRVLTGLVQGTVYPCVHTLLAKWVPRTER----GLLTTGVYSGAQFGTAVIL 169
             ||.:.|...:.:.||:.||.:|.:.|..:.:||.|.|..||    .|.|||.......|..|
 Worm   165 YIATRFGPYPVFISRVIMGLGEGFILPANNAILANWFPSAERSTAISLFTTGNQMAGAGGNPV-- 227

  Fly   170 VTSGFIFESSMGWPGLFYLSGGLSLAWALLFFWQAANEPVTASRISKGEVEYIES--LTGSNSSS 232
              :..:..||.|||.:||.:..:|..|::.:|..|:|:|.....::|.|.:|:::  :..||.::
 Worm   228 --AASLCASSFGWPSIFYFASIVSTIWSVCWFLTASNQPSKCKVMTKTERDYLDANVVRRSNKTN 290

  Fly   233 QSMPVPWMSIFRSPAFYGLLAAHCGFTWGFYTLLTE--MPTYMSMVLQLNVKSNAFLSSLPYFAM 295
            :|:.||:..|.:||||...|.  |.|...|...|.:  :|.|...||.|.|.:|...:|:|
 Worm   291 RSLVVPYSKILKSPAFLAQLL--CQFVINFIVTLLQIYLPNYFKDVLHLGVIANGTYTSVP---- 349

  Fly   296 GLLCFVVSPISDLLINRG----TISITTARKLFNSIGQWGPMACLIGLGY-MTADEKTWAILLLT 355
            .::.|.:..:..:.|:|.    .||.|...||..||..:|....||.:.| :.....|...:...
 Worm   350 NIVNFALKIVWGITIDRAKEKKIISGTFGVKLSQSIANFGGALFLILITYFVDCTNPTLGFVFFC 414

  Fly   356 LAVGINAGCSCGYLINHIDLSPNFAGPMMGVTNGIAGVTSIIAPLVVGAIVSDEEDPSQWRMVFF 420
            :..|.......|:..:.:.|:|.:...|..::...|.:..:..|.:|| ::..:...|:|:.:|.
 Worm   415 MMYGCMGTLVSGFYTSLLSLAPKYTATMSSISVFCAMMGRLATPAIVG-LIKKQNTLSEWQTLFL 478

  Fly   421 ITGGIYLVCNTIFVIFGKATIQIWNEPPSTSSTMTLRSHQENDSKSIVP--TSDKDI 475
            :.....::|..:|::||...:|.|..........||.......|...:|  |.|:||
 Worm   479 VCAAANIICGAVFLVFGSGELQEWGLEDEAKEMKTLAEKTPLASIQNLPADTEDQDI 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS12	NP_610332.3	MFS_SLC17	22..437	CDD:340876	114/470 (24%)
slc-17.4	NP_503071.2	MFS	34..495	CDD:475125	114/470 (24%)