DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS12 and R10D12.1

DIOPT Version :9

Sequence 1:	NP_610332.3	Gene:	MFS12 / 35745	FlyBaseID:	FBgn0033234	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_506456.1	Gene:	R10D12.1 / 179888	WormBaseID:	WBGene00011185	Length:	485	Species:	Caenorhabditis elegans

Alignment Length:	454	Identity:	95/454 - (20%)
Similarity:	184/454 - (40%)	Gaps:	27/454 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 EDKARPGGLGVRHWQAVLLFVGMMINYFQRVNISAAIVPMTQSTA-----GAPFYTWDTSDKSLI 66
            :.|.:||.:......:.:|.:..:::.....|.:...:|.:..|.     ...|..:...:|:::
Worm    27 DSKDQPGYVRYLIMISTMLCLTSLMSNVVCFNFTVLCMPGSGETGELVGNRTHFVGYTRQEKTVL 91

  Fly    67 LSSFFWGYVVSQVPAGLLAKRFGAKLVLGLATAIGGILCFFHPIAAKSGWQSICVLRVLTGLVQG 131
            ||:...|.|....|..:...:.|.|.|...:..:..|..|..||.|...:....:||.:.||...
Worm    92 LSTVAIGAVCGVFPVIIGISKLGLKKVFMTSGVLTAISTFLIPILAPLHFHLFIMLRFVQGLSYA 156

  Fly   132 TVYPCVHTLLAKWVPRTERGLLTTGVYSGAQFGTAVILVTSGFIFESSMGWPGLFYLSGGLSLAW 196
            ..:|.|..:.:.|....::||....:.:..|..:...:..:|.:..|..||..:|||...:||..
Worm   157 ACFPAVGAITSSWASLAQQGLFIAALTTFGQTSSIFSMPVAGELCTSVFGWKSVFYLHAIISLVV 221

  Fly   197 ALLFFWQAANEPVTASRISKGEVEYIESLTGSNSSSQSMPVPWMSIFRSPAFYGLLAAHCGFTWG 261
            ..::|....:.|.....:...|:..||.....:...:....|::.|..:|:.:|:.....|....
Worm   222 FTIWFALFTDSPEDNKLVRPAELAEIEFGKSEDEIHEHSNTPYLEILTTPSVWGIWIGAFGDLIA 286

  Fly   262 FYTLLTEMPTYMSMVLQLNVKSNAFLSSLPYFAMGLLCFVVSPISDLLINRGTISITTARKLFNS 326
            ...:....|.::..|...:.:...|.:::|......:.......||.:..   ||.||..:::|:
Worm   287 VQLIHIYSPVFLHDVGGYSFEKTGFAAAVPVLFQFFVKMFAGHSSDKVHG---ISETTKLRIYNT 348

  Fly   327 IGQWGPMACLIGLGYMTADEKTWAILLLTLAVGI---NAG--CSCGYLI----NHIDLSPNFAGP 382
            |........|:.||::...:....::|:|||.|:   |.|  ..|..|:    ||.
Worm   349 IALGASAIFLVSLGFVKQGQGVLGLVLMTLATGMFGFNGGGFSKCAALVSRQYNHF--------- 404

  Fly   383 MMGVTNGIAGVTSIIAPLVVGAIVSDEEDPSQWRMVFFITGGIYLVCNTIFVIFGKATIQIWNE 446
            :|.:...:..::.|:.|::|..|: .....::||:|||:...|.|:||.||.....|....|.:
Worm   405 VMAIQQILVCLSMIVCPIIVSTIL-QHGTTAEWRIVFFVHAAILLICNAIFCWLATAKPAPWTD 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS12	NP_610332.3	MFS	23..436	CDD:119392	90/426 (21%)
MFS12	NP_610332.3	2A0114euk	25..447	CDD:129972	92/436 (21%)
R10D12.1	NP_506456.1	MFS	55..455	CDD:391944	88/412 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810