DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS12 and T27D12.1

DIOPT Version :9

Sequence 1:	NP_610332.3	Gene:	MFS12 / 35745	FlyBaseID:	FBgn0033234	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_001254320.1	Gene:	T27D12.1 / 174820	WormBaseID:	WBGene00012085	Length:	502	Species:	Caenorhabditis elegans

Alignment Length:	499	Identity:	117/499 - (23%)
Similarity:	197/499 - (39%)	Gaps:	92/499 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 WQAVLLFVGMMINYFQRVNISAAIVPM----------TQSTAGAPFYTWDTSDKSLILSSFFWGY 74
            |..:|.|     |:        |:|.|          ...||....:|  ::..||.::......
Worm    49 WSNILAF-----NF--------AVVCMDDDDSEMGASLNGTARKTHFT--STQNSLAMAIVAIAA 98

  Fly    75 VVSQVPAGLLAKRFGAKLV---LGLATAIGGILCFFHPIAAKSGWQSICVLRVLTGLVQGTVYPC 136
            ::...|...|....|.:.|   ||:.:|:..:|.   |::.:.|:.....:|.|.|......:|.
Worm    99 LLGNFPIVQLVGMVGIRTVFAGLGILSAVSTLLI---PLSIRMGFYYFLAVRFLQGFAFAANFPV 160

  Fly   137 VHTLLAKWVPRTERGLLTTGVYSGAQFGTAVILVTSGFIFESSMGWPGLFYLSGGLSLAWALLFF 201
            :.:..|||....:.||..:.:.:..|...|:.:..||.:. |:..||.:||..|.:||   |||.
Worm   161 IGSFCAKWSYFKQNGLFVSSLVAYVQLSPAITMPASGALC-SAFKWPSIFYAHGAVSL---LLFV 221

  Fly   202 WQA---ANEP--------VTASRISKGEVEYIESLTGSNSSSQSMPVPWMSIFRSPAFYGLLAAH 255
            ..|   .|.|        |...:||.|::..::       ......||:..|.::||.:.:..|
Worm   222 TYALFYRNSPQKHPFVGNVELKKISIGKIAAVD-------KRALKKVPYGPILKTPAIWAVWVA- 278

  Fly   256 CGFTWGFYTLLTEM----PTYMSMVLQLNVKSNAFLSSLP---YFAMGLLCFVVSPISDLLINRG 313
               ..|.:|.:..|    |.|:|.||...|.|....:::|   .|:..|:|   ...||.|.
Worm   279 ---AIGNFTCVNMMFLFSPIYLSKVLGFPVHSTGITAAIPPFLQFSSKLIC---GAASDRLT--- 334

  Fly   314 TISITTARKLFNSIGQWGPMACLIGLGYMTADEKTWAILLLTLAVGINAGCSCGYLINHIDLSPN 378
            .:|.....:|||::...|....|..|.:|..:.|...:::|..|..:....:.|:.
Worm   335 CLSEGVKFRLFNTLAFVGSAGFLCVLAFMGDEHKRNNMIVLGCAAAMLGATTGGFF--------- 390

  Fly   379 FAGPMMG------VTNGIA---GVTSIIAPLVVGAIVSDEEDPSQWRMVFFITGGIYLVCNTIFV 434
            .|||::.      ||..|:   .:|.:|.|..|.|:..:... .:|:.||.|||.:.::.|..||
Worm   391 KAGPVLSKQYSHFVTGNISLGITITMLIVPFFVNALTPNNTQ-EEWKYVFLITGAVMVITNIFFV 454

  Fly   435 IFGKATIQIWNEPP--STSSTMTLRSHQ-ENDSKSIVPTSDKDI 475
            ||.:.....|....  ..||......|. .|...|.:..:.:|:
Worm   455 IFVRGDPCEWTSDSFHRASSVADFEQHHIRNTGISTISHNVEDV 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS12	NP_610332.3	MFS	23..436	CDD:119392	107/452 (24%)
MFS12	NP_610332.3	2A0114euk	25..447	CDD:129972	109/461 (24%)
T27D12.1	NP_001254320.1	MFS	56..456	CDD:391944	105/443 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920