DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS12 and slc-17.6

DIOPT Version :9

Sequence 1:	NP_610332.3	Gene:	MFS12 / 35745	FlyBaseID:	FBgn0033234	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_490947.2	Gene:	slc-17.6 / 171781	WormBaseID:	WBGene00017398	Length:	546	Species:	Caenorhabditis elegans

Alignment Length:	457	Identity:	108/457 - (23%)
Similarity:	205/457 - (44%)	Gaps:	26/457 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 VRHWQAVLLFVGMMINYFQRVNISAAIVPMTQSTAGAPFY-----TWDTSDKSLILSSFFWGYVV 76
            :|...|:|:....::....|.....|:|.:.:|..|. |:     .|...:::.|.:||:.|..:
Worm    25 IRFQTALLISAACVVFGLMRTCFGMAMVDIVRSGNGT-FHPDLHMEWSGDEQANIHTSFYIGAFI 88

  Fly    77 SQVPAGLLAKRFGAKLVLGLATAI---GGILCFFHPIAAKSGWQSICVLRVLTGLVQGTVYPCVH 138
            :..|:..|||:.|.|.:|..|..:   |.:|..|..|..:| :..:..:|::.|...|.|.|...
Worm    89 AVFPSEFLAKKLGPKNLLSFALLLNIFGSLLTPFSAIYLRS-YFPVAAIRLIMGFGYGFVIPAGS 152

  Fly   139 TLLAKWVPRTERGLLTTGVYSGAQFGTAVILVTSG-----FIFESSMGWPGLFYLSGGLSLAWAL 198
            .|::.|.|.:|:........:|.|.|.||.:..:.     ..||   |||.:|.:.|.:...:.:
Worm   153 VLISSWFPLSEKSTAMAIFTTGNQIGIAVSMFLTAKLCQLHFFE---GWPLVFIVYGLIGAVFLV 214

  Fly   199 LFFWQAANEPVTASRISKGEVEYIESLTGSNSSSQSM--PVPWMSIFRSPAFYGLLAAHCGFTWG 261
            ::..:.|::|..:..|:..|:.||:......:.::::  ..|:|.|..:.....:.|  |.|...
Worm   215 IWHVRLADKPRESKYITATELTYIKGGKQRRNRAETIVRATPYMKIILNGCVCAICA--CSFAQS 277

  Fly   262 F--YTLLTEMPTYMSMVLQLNVKSNAFLSSLPYFAMGLLCFVVSPISDLLINRGTISITTARKLF 324
            |  ..|:|.:|.|..:..::|:..|...||||:|...:...:.:.|:|.:..| .::.|...|:.
Worm   278 FVLVALVTYLPKYNQIAFKMNLTHNGIWSSLPFFIQMITKLLFAIIADKVKQR-KVNATAVTKVS 341

  Fly   325 NSIGQWGPMACLIGLGYMTADEKTWAILLLTLAVGINAGCSCGYLINHIDLSPNFAGPMMGVTNG 389
            |:|..:.....::...|...|......|.:.:::...:....||..:.:.::|.|...:......
Worm   342 NAIASFASAIFIVIAAYGPFDSAELVQLSIIVSMAAFSAYVPGYNTSIVTVAPQFTAFISSYAQL 406

  Fly   390 IAGVTSIIAPLVVGAIVSDEEDPSQWRMVFFITGGIYLVCNTIFVIFGKATIQIWNEPPSTSSTM 454
            .|.:.|.:||:|:|.|.| .....:|:..|:...|:..|...||.|||....:.|.|.||.:::.
Worm   407 YAQIASTLAPIVIGRITS-HGTIYEWKCAFYSLAGVLAVTGLIFQIFGHGRTEPWGETPSNATSA 470

  Fly   455 TL 456
            .|
Worm   471 RL 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS12	NP_610332.3	MFS	23..436	CDD:119392	98/429 (23%)
MFS12	NP_610332.3	2A0114euk	25..447	CDD:129972	101/438 (23%)
slc-17.6	NP_490947.2	MFS	30..453	CDD:391944	100/431 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010