DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS12 and Slc17a1

DIOPT Version :9

Sequence 1:	NP_610332.3	Gene:	MFS12 / 35745	FlyBaseID:	FBgn0033234	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_598238.2	Gene:	Slc17a1 / 171080	RGDID:	620099	Length:	465	Species:	Rattus norvegicus

Alignment Length:	473	Identity:	153/473 - (32%)
Similarity:	230/473 - (48%)	Gaps:	47/473 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 KARPGGLGVRHWQAVLLFVGMMINYFQRVNISAAIVPMTQST----------------AGAPFYT 57
            |..||....|:..|:||....::...|||.::..:|.|...|                ...|.::
  Rat     8 KKVPGFCSFRYGLAILLHFCNIVIMAQRVCLNLTMVAMVNKTEPPHLSNKSVAEMLDNVKNPVHS 72

  Fly    58 WDTSDKSLILSSFFWGYVVSQVPAGLLAKRFGAKLVLGLATAIGGILCFFHPIAAKSGWQSICVL 122
            |....:.|||||.|.|.||.|||.|.|:..:..|.::|.:..:..:|....|.||:.|...:.|.
  Rat    73 WSLDIQGLILSSVFLGMVVIQVPVGYLSGAYPMKKIIGSSLFLSSVLSLLIPPAAQVGAALVIVC 137

  Fly   123 RVLTGLVQGTVYPCVHTLLAKWVPRTERGLLTTGVYSGAQFGTAVILVTSGFIFESSMGWPGLFY 187
            |||.|:.||.|....|.:..||.|..|||.||:...||...|..:.|:.||||.: .:|||.:||
  Rat   138 RVLQGIAQGAVSTGQHGIWVKWAPPLERGRLTSMTLSGFVMGPFIALLVSGFICD-LLGWPMVFY 201

  Fly   188 LSG----GLSLAWALLFFWQAANEPVTASRISKGEVEYIES--LTGSNSSSQSMPVPWMSIFRSP 246
            :.|    .|||.|.:|||....|.|.    :|..|.:||.|  :...:|..||:|:  .::.:|.
  Rat   202 IFGIVGCVLSLFWFILFFDDPNNHPY----MSSSEKDYITSSLMQQVHSGRQSLPI--KAMLKSL 260

  Fly   247 AFYGLLAAHCGFTWGFYTLLTEMPTYMSMVLQLNVKSNAFLSSLPYFAMGLLCFVVSPISDLLIN 311
            ..:.::.....|.|....|:|..||::|..|.:||:.|..||||||....:...|...:||.|::
  Rat   261 PLWAIILNSFAFIWSNNLLVTYTPTFISTTLHVNVRENGLLSSLPYLLAYICGIVAGQMSDFLLS 325

  Fly   312 RGTISITTARKLFNSIGQWGP---MACLIGLGYMTADEKTWAILLLTLAVGINAGCSCGYLINHI 373
            |...|:...||||.::|.:.|   :.||:.|.|....    .::.||||....:...||.|||.:
  Rat   326 RKIFSVVAVRKLFTTLGIFCPVIFVVCLLYLSYNFYS----TVIFLTLANSTLSFSFCGQLINAL 386

  Fly   374 DLSPNFAGPMMGVTN--GIAG--VTSIIAPLVVGAIVSDEEDPS-QWRMVFFITGGIYLVCNTIF 433
            |::|.:.|.:..||.  ||.|  ::|.:|.|::      .:||. .|...||:..||.:.|...:
  Rat   387 DIAPRYYGFLKAVTALIGIFGGLISSTLAGLIL------NQDPEYAWHKNFFLMAGINVTCLAFY 445

  Fly   434 VIFGKATIQIWNEPPSTS 451
            ::|.|..||.|.:...|:
  Rat   446 LLFAKGDIQDWAKETKTT 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS12	NP_610332.3	MFS	23..436	CDD:119392	142/442 (32%)
MFS12	NP_610332.3	2A0114euk	25..447	CDD:129972	146/451 (32%)
Slc17a1	NP_598238.2	2A0114euk	1..464	CDD:129972	153/473 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG47714
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920