Protein Alignment MFS12 and slc17a8

DIOPT Version :10

• Sequence 1: NP_610332.3
• Gene: MFS12 / 35745
• FlyBaseID: FBgn0033234
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: XP_002936892.1
• Gene: slc17a8 / 100489470
• XenbaseID: XB-GENE-988965
• Length: 588
• Species: Xenopus tropicalis
• Alignment Length: 450
• Identity: 137/450 - (30%)
• Similarity: 222/450 - (49%)
• Gaps: 16/450 - (3%)

  Fly    14 GLGVRHWQAVLLFVGMMINYFQRVNISAAIVPMTQSTA----GAP-----FYTWDTSDKSLILSS 69
            |:..|:..|::..:|..|::..|.|:..|||.|..:..    |.|     .:.||.....||..|
 Frog    71 GIPKRYIIAMMSGLGFCISFGIRCNLGVAIVEMVNNNTVYVDGKPEMQKAQFNWDPETVGLIHGS 135

  Fly    70 FFWGYVVSQVPAGLLAKRFGAKLVLGLATAIGGILCFFHPIAAKSGWQSICVLRVLTGLVQGTVY 134
            |||||:::|:|.|.:|.:..|..|.|.|..:..||....|.||:..:..:..:|||.|||:|..|
 Frog   136 FFWGYIITQIPGGFIANKLAANRVFGAAIFLTSILNMLIPSAARVHFGCVISVRVLQGLVEGVTY 200

  Fly   135 PCVHTLLAKWVPRTERGLLTTGVYSGAQFGTAVILVTSGFIFESSMGWPGLFYLSGGLSLAWALL 199
            |..|.:.:||.|..||..|.|..:.|:..|..:.:..:|.:.: .:|||.:||:.|...:.|.:.
 Frog   201 PACHGMWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGVLVQ-YIGWPSVFYIYGVFGMCWYVF 264

  Fly   200 FFWQAANEPVTASRISKGEVEYIESLTGSNS---SSQSMPVPWMSIFRSPAFYGLLAAHCGFTWG 261
            :...|...|.....|:..|..|||:..|..|   ::.....||...|.|...|.::.|:...:|.
 Frog   265 WLLHATESPAAHPSITFEERTYIETSIGEGSNLVTTGKFKTPWKKFFTSMPVYAIIVANFCRSWT 329

  Fly   262 FYTLLTEMPTYMSMVLQLNVKSNAFLSSLPYFAMGLLCFVVSPISDLLINRGTISITTARKLFNS 326
            ||.||...|.|...|....:.....||::|:..|.::..|...::|.|.:|..:|.||.||:.|.
 Frog   330 FYLLLISQPAYFEEVFGFPISKVGLLSAVPHMVMTIIVPVGGQLADFLRSRKILSTTTVRKIMNC 394

  Fly   327 IGQWGPMACLIGLGYMTADEKTWAILLLTLAVGINAGCSCGYLINHIDLSPNFAGPMMGVTNGIA 391
            .|.......|:.:||  :..|..:|..|.||||.:.....|:.:||:|::|.:|..:||::||:.
 Frog   395 GGFGMEATLLLVVGY--SHTKAISISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVG 457

  Fly   392 GVTSIIAPLVVGAIVSDEEDPSQWRMVFFITGGIYLVCNTIFVIFGKATIQIWNEPPSTS 451
            .::.::.||:|||:..: :...:|:.||.|...::......:.||.....|.|.:|.|.|
 Frog   458 TLSGMVCPLIVGAMTKN-KTREEWQNVFLIAAIVHYSGVIFYGIFASGEKQEWADPESLS 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS12	NP_610332.3	MFS_SLC17	22..437	CDD:340876	129/426 (30%)
slc17a8	XP_002936892.1	MFS_SLC17A6_7_8_VGluT	79..502	CDD:340940	129/426 (30%)