DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS12 and slc17a7b

DIOPT Version :9

Sequence 1:	NP_610332.3	Gene:	MFS12 / 35745	FlyBaseID:	FBgn0033234	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	XP_009295917.2	Gene:	slc17a7b / 100331980	ZFINID:	ZDB-GENE-131125-32	Length:	585	Species:	Danio rerio

Alignment Length:	467	Identity:	139/467 - (29%)
Similarity:	227/467 - (48%)	Gaps:	23/467 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 EPSEDKARP------GGLGVRHWQAVLLFVGMMINYFQRVNISAAIVPMTQSTA----GAPF--- 55
            |..|:|..|      .||..|:..|:|..:|..|::..|.|:..|:|.|..:..    |.|:
Zfish    42 ELQEEKELPVVDCTCFGLPRRYIIAILSGLGFCISFGIRCNLGVAVVSMVNNHTVYRDGKPYIVK 106

  Fly    56 --YTWDTSDKSLILSSFFWGYVVSQVPAGLLAKRFGAKLVLGLATAIGGILCFFHPIAAKSGWQS 118
              ::||.....:|..||||||:|:|:|.|.:.::|.|..|.|.|.....||....|.||:..:..
Zfish   107 AQFSWDPETVGMIHGSFFWGYIVTQIPGGFICQKFAANRVFGFAVVSTSILNMMIPTAARMHFGC 171

  Fly   119 ICVLRVLTGLVQGTVYPCVHTLLAKWVPRTERGLLTTGVYSGAQFGTAVILVTSGFIFESSMGWP 183
            :.::|:|.|||:|..||..|.:.|||.|..||..|.|..:.|:..|..:.:..:|.:.:.| ||.
Zfish   172 VILVRILQGLVEGVSYPACHGIWAKWAPPLERSRLATTAFCGSYAGAVIAMPLAGVLVQYS-GWS 235

  Fly   184 GLFYLSGGLSLAWALLFFWQAANEPVTASRISKGEVEYIESLTGSNSS----SQSMPVPWMSIFR 244
            .:||:.|...:.|.|.:...:...|.....|:..|.:|||...|.::.    ......||...|.
Zfish   236 SVFYVYGSFGVCWYLFWILVSYESPAAHPTITPEERKYIEDAIGESAGLVNPLTKFNTPWRQFFT 300

  Fly   245 SPAFYGLLAAHCGFTWGFYTLLTEMPTYMSMVLQLNVKSNAFLSSLPYFAMGLLCFVVSPISDLL 309
            |...|.::.|:...:|.||.||...|.|...|.:..:.....||:||:..|.::..:...::|.|
Zfish   301 SMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFKFEISKVGILSALPHLVMTIVVPIGGQLADYL 365

  Fly   310 INRGTISITTARKLFNSIGQWGPMACLIGLGYMTADEKTWAILLLTLAVGINAGCSCGYLINHID 374
            .....::.|..|||.|..|.......|:.:|:  :..|..||..|.||||.:.....|:.:||:|
Zfish   366 RTHNLMTTTNVRKLMNCGGFGLEATFLLVVGF--SHTKGVAISFLVLAVGFSGFAISGFNVNHLD 428

  Fly   375 LSPNFAGPMMGVTNGIAGVTSIIAPLVVGAIVSDEEDPSQWRMVFFITGGIYLVCNTIFVIFGKA 439
            ::|.:|..:||::||:..::.::.||:|||:..: :...:|:.||.|...::......:.:|...
Zfish   429 IAPRYASILMGISNGVGTLSGMVCPLIVGAMTKN-KTREEWQYVFLIASLVHYGGVIFYGLFASG 492

  Fly   440 TIQIWNEPPSTS 451
            ..|.|.||.:||
Zfish   493 EKQPWAEPENTS 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS12	NP_610332.3	MFS	23..436	CDD:119392	124/425 (29%)
MFS12	NP_610332.3	2A0114euk	25..447	CDD:129972	126/434 (29%)
slc17a7b	XP_009295917.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582490
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.750