DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kdm4A and PHF14

DIOPT Version :9

Sequence 1:	NP_610331.1	Gene:	Kdm4A / 35744	FlyBaseID:	FBgn0033233	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_001007158.1	Gene:	PHF14 / 9678	HGNCID:	22203	Length:	948	Species:	Homo sapiens

Alignment Length:	98	Identity:	25/98 - (25%)
Similarity:	38/98 - (38%)	Gaps:	20/98 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   365 EYEKQENLRAAKSEEESPQKRGCSLAGNGCERNAESAEDVD-DKASVSS--YSSCRQLQPVVKLR 426
            |.|..|..|..|.:|:..:|          |:..|...:.: :||:||.  .:|.....|.....
Human   104 EEENGERPRKKKEKEKEKEK----------EKEKEKEREKEKEKATVSENVAASAAATTPATSPP 158

  Fly   427 KLPTIASVPEPSSAPKRYDFNTEAVVRVKRLWN 459
            .:.|..|||..::|       ||..|...:.||
Human   159 AVNTSPSVPTTTTA-------TEEQVSEPKKWN 184

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kdm4A	NP_610331.1	JmjN	17..59	CDD:301729
Kdm4A	NP_610331.1	JmjC	182..298	CDD:202224
PHF14	NP_001007158.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	22..302		25/98 (26%)
		PHD1_PHF14	321..377	CDD:277036
		ePHD_PHF14	385..498	CDD:277144
		PHD2_PHF14	727..776	CDD:277037
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	812..867
		PHD3_PHF14	870..918	CDD:277038
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5141
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900