DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Kdm4A and PKDM7D

DIOPT Version :9

Sequence 1:	NP_610331.1	Gene:	Kdm4A / 35744	FlyBaseID:	FBgn0033233	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_172338.5	Gene:	PKDM7D / 837384	AraportID:	AT1G08620	Length:	1223	Species:	Arabidopsis thaliana

Alignment Length:	389	Identity:	105/389 - (26%)
Similarity:	151/389 - (38%)	Gaps:	102/389 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 FRPSYEEFQNFSAYIEYIESRGAHLAGLAKIQPPAEWVP-------------------------- 59
            |.||.|||::...||..|... |...|:.:|.||..|.|
plant   163 FYPSEEEFEDTLNYIAKIRPE-AEKYGICRIVPPPSWKPPCPLKEKQVWEGSKFTTRVQRVDKLQ 226

  Fly    60 ----------------------RKSGYDIDNINMTIPAPICQVVTGAHGVYQQINIQQRRQMTLR 102
                                  .|.|.|.....|..|   |...||.:.: :....:.....||:
plant   227 NRSSMKKISKLPNQMRKKKRKCMKMGMDSVTNGMGDP---CSASTGMNEL-ETFGFEPGPGFTLK 287

  Fly   103 QFM--------------EKANSELHQTPRHFD-----YDDLERKYW----KNITYISPLYAADVK 144
            .|.              |.:..:..:.....|     .:|:|.:||    |....|..||.||::
plant   288 DFQKYADEFKAQYFKKSETSTDDKCKVDNSIDCWEPALEDVEGEYWRIVDKATEEIEVLYGADLE 352

  Fly   145 ---------------GSLSDED---LDVWNIGRL----DTILNLVNTDYNIIIDGVNTAYLYFGM 187
                           .:.|.||   ...||:...    .::|....:|    |.||...:||.||
plant   353 TGVFGSGFPKISSSHNASSSEDKYAKSGWNLNNFPRLPGSLLKYEGSD----ISGVLVPWLYIGM 413

  Fly   188 WKSSFAWHTEDMDLYSINYLHFGAPKTWYAIPPAYGRRLEKLANETFSENYQECNAYLRHKMTMI 252
            ..|||.||.||..|||:||:|:||||.||.:......:||:...:...:.::|....|...:|.:
plant   414 CFSSFCWHVEDHHLYSLNYMHWGAPKLWYGVGGKDAVKLEEAMRKHLPDLFEEQPDLLHKLVTQL 478

  Fly   253 SPKVLRQHNIPYNKITQEAGEIMITFPFGYHAGFNHGFNGAESTNFASKRWIEYGKRASICRCR 316
            ||..|:...:|.::..|.|||.::|||..||||||.|||.||:.|.|...|:.:|:.|....|:
plant   479 SPSKLKTAGVPVHRCVQHAGEFVLTFPRAYHAGFNSGFNCAEAVNVAPVDWLPHGQIAIELYCQ 542

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kdm4A	NP_610331.1	JmjN	17..59	CDD:301729	15/37 (41%)
Kdm4A	NP_610331.1	JmjC	182..298	CDD:202224	50/115 (43%)
PKDM7D	NP_172338.5	JmjN	161..193	CDD:367058	11/30 (37%)
		JmjC	408..524	CDD:334913	50/115 (43%)
		zf-C5HC2	631..683	CDD:367254
		trpS	<807..>860	CDD:272975
		FYRN	1002..1046	CDD:128814
		FYRC	1052..1146	CDD:197781
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	100	1.000	Inparanoid score	I2177
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.920