Protein Alignment Kdm4A and Kdm4dl2

DIOPT Version :9

• Sequence 1: NP_610331.1
• Gene: Kdm4A / 35744
• FlyBaseID: FBgn0033233
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: XP_008764220.1
• Gene: Kdm4dl2 / 500944
• RGDID: 1563367
• Length: 460
• Species: Rattus norvegicus
• Alignment Length: 478
• Identity: 217/478 - (45%)
• Similarity: 282/478 - (58%)
• Gaps: 80/478 - (16%)

  Fly     9 DEEQNKVPRIMTFRPSYEEFQNFSAYIEYIESRGAHLAGLAKIQPPAEWVPRKSGYDIDNINMTI 73
            |..||....||||.|:.|||.:|..||.|:||:|||.||:||:.||.:|..|:|..|:  ::|:|
  Rat     7 DVSQNPGCSIMTFCPTMEEFSDFCKYIAYMESQGAHRAGVAKVIPPKDWKRRQSYEDV--MDMSI 69

  Fly    74 PAPICQVVTGAHGVYQQINIQQRRQMTLRQFMEKANSELHQTPRHFDYDDLERKYWKNITYISPL 138
            |||:.|||:|..||:.|.: ::::.||:.::.|.|.|:.:|||.|.|::|||||||||..:.||:
  Rat    70 PAPLQQVVSGKAGVFTQYH-KKKKAMTVGKYRELAESKQYQTPPHLDFEDLERKYWKNRLFGSPI 133

  Fly   139 YAADVKGSLSDEDLDVWNIGRLDTILNLVNTDYNIIIDGVNTAYLYFGMWKSSFAWHTEDMDLYS 203
            |.|||.|||.||:...||:|.|.::|:::..|..|:|:||||.||||||||:|||||||||||||
  Rat   134 YGADVSGSLFDENTQHWNVGHLGSLLDVLKQDRGIVIEGVNTPYLYFGMWKTSFAWHTEDMDLYS 198

  Fly   204 INYLHFGAPKTWYAIPPAYGRRLEKLANETFSENYQECNAYLRHKMTMISPKVLRQHNIPYNKIT 268
            |||||||.||||||:||.:|||||.||.|.|..:.|.|.|:||||:.:|||.||:::.||:.:||
  Rat   199 INYLHFGQPKTWYAVPPEHGRRLELLAKELFPGSSQGCQAFLRHKVALISPTVLKENGIPFGRIT 263

  Fly   269 QEAGEIMITFPFGYHAGFNHGFNGAESTNFASKRWIEYGKRASICRCRSDMVKISMETFVRRFQP 333
            |||||.|:|||:|||||||||||.||:.|||:.|||:|||.||.|.|....|..||:.|....||
  Rat   264 QEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKVASQCSCGEARVSFSMDAFEGLLQP 328

  Fly   334 ERYD----------------------------------------------NWLKGQDMGC----- 347
            |.|:                                              |||:.....|
  Rat   329 EPYEMWKQQGNQRAMDPLALTSGPRQELTLGIDQLKPDSKQNGSHSGPRRNWLRRGQKSCPYRKV 393

  Fly   348 HPEEPGKICAAAPPTLNEYEKQENLRAAKSEEESPQKRGCSLAGNGCERNAESAEDVDDKASVSS 412
            |.|.|      .|||       ..|.|.:|   .||...||...:|..:......||   .:|:.
  Rat   394 HAESP------CPPT-------GKLLAPRS---VPQGTRCSKQASGSSKTPAICADV---LAVNH 439

  Fly   413 YSSCRQLQPVVKLRKLPTIASVP 435
            ..:||.|.     |.|  |.|:|
  Rat   440 SQACRILD-----RSL--IVSLP 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kdm4A	NP_610331.1	JmjN	17..59	CDD:301729	24/41 (59%)
		JmjC	182..298	CDD:202224	83/115 (72%)
Kdm4dl2	XP_008764220.1	JmjN	16..56	CDD:128818	23/39 (59%)
		JmjC	177..293	CDD:396791	83/115 (72%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1186832at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010