DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kdm4A and brd1b

DIOPT Version :9

Sequence 1:	NP_610331.1	Gene:	Kdm4A / 35744	FlyBaseID:	FBgn0033233	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	XP_005163199.1	Gene:	brd1b / 100009661	ZFINID:	ZDB-GENE-070209-98	Length:	1168	Species:	Danio rerio

Alignment Length:	161	Identity:	37/161 - (22%)
Similarity:	57/161 - (35%)	Gaps:	55/161 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   347 CHPEEPGKICAAAPPTLNEYEKQEN---LRAAKSEEESPQKRGCSLAGNGCERNAESAEDVDDKA 408
            |.|..|... ...|.|:.:..|.:|   .:||..|    :.:||....|   :..||..|.
Zfish   383 CCPHTPNGF-VRRPLTIYDDSKSKNGVCQKAAHRE----RVKGCQKKKN---KKPESEPDT---- 435

  Fly   409 SVSSYSSCRQLQPVVKLRKLPTIASVPEPSSAPKRYDFNT---EAVVRVKRLWNELPCPDRGANL 470
                              .:||::.   ||..||  .|||   :..|:.||::.|        .:
Zfish   436 ------------------VVPTVSG---PSITPK--SFNTILNQVSVQKKRMFVE--------RV 469

  Fly   471 LTNGVVKNTKR------MRFQTKVLTLDDED 495
            |:..::|...|      .|.||.:.|..|.:
Zfish   470 LSYWMLKRQSRNGVPLIRRLQTAIQTQKDPE 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kdm4A	NP_610331.1	JmjN	17..59	CDD:301729
Kdm4A	NP_610331.1	JmjC	182..298	CDD:202224
brd1b	XP_005163199.1	EPL1	45..193	CDD:287484
		PHD_BRPF2	211..264	CDD:277147
		PHD_SF	268..386	CDD:304600	1/2 (50%)
		Bromo_brd1_like	559..656	CDD:99944
		PWWP	1042..1157	CDD:295359
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5141
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900