DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cul1 and AT4G12100

DIOPT Version :9

Sequence 1:	NP_523655.1	Gene:	Cul1 / 35742	FlyBaseID:	FBgn0015509	Length:	774	Species:	Drosophila melanogaster
Sequence 2:	NP_192947.1	Gene:	AT4G12100 / 826818	AraportID:	AT4G12100	Length:	434	Species:	Arabidopsis thaliana

Alignment Length:	362	Identity:	86/362 - (23%)
Similarity:	151/362 - (41%)	Gaps:	64/362 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 NRSGNSQTTQKLVNLDDIWSELVEGIMQVFEHEKSLTRSQYMRFYTHVYDYCTSVSAAPSGRSSG 66
            |...::|...||. |...|..|...|..:.:.::.......:.|        |::..|......|
plant    64 NSVKDTQDRNKLY-LAKAWDLLKPAIKIILDDDEYKKPGDVLCF--------TTIFRAVKRACLG 119

  Fly    67 KTGGAQLVGKKLYDRLEQFLKSYLSELLTKF-KAISGEE---VLLSRYTKQWKSYQFSSTVLDGI 127
            ....::||    ::.::...:.:::||:... |..||.:   |.|.....:|..::...:::..:
plant   120 DPRQSELV----FNLVKHECEPHIAELIQSLEKNCSGSDDPSVFLPHVYNRWLDFKRKMSLVSDV 180

  Fly   128 CNYLNRN----WVKRECEEGQKGIYKIYRLALVAWKGHLFQVLNEPVTKAVLKSIEEERQGKLIN 188
            ..|...|    |     :.|||..:|...:|         ..|.:.|...:|:.|.:||.||..|
plant   181 AMYQTLNGLTLW-----DVGQKLFHKQLSMA---------PQLQDQVITGILRLITDERLGKAAN 231

  Fly   189 RS--LVRDVIECYVELSFNEEDTDAEQQKLSVYKQNFENKFIADTSAFYEKESDAFLSTNTVTEY 251
            .:  |::::::.:          ..:.|...|||    :.|:..||.||.:|::..|..:.::.|
plant   232 NTSDLLKNLMDMF----------RMQWQCTYVYK----DPFLDSTSKFYAEEAEQVLQRSDISHY 282

  Fly   252 LKHVENRL--EEETQRVRGFNSKNGLSYLHETTADVLKSTCEEVLIEKHLKIFHTEFQNLLNADR 314
            ||:||...  |||......|...:..|.|.:    ||||.    |:|.|.......|..|::...
plant   283 LKYVERTFLAEEEKCDKHYFFFSSSRSRLMK----VLKSQ----LLEAHSSFLEEGFMLLMDESL 339

  Fly   315 NDDLKRMYSLVAL-SSKNLTDLKSILENHILHQGTEA 350
            .|||:|||.|.:: .|::..|  .||..:||.:|..|
plant   340 IDDLRRMYRLFSMVDSEDYID--RILRAYILAKGEGA 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cul1	NP_523655.1	Cullin	21..669	CDD:279260	80/343 (23%)
		CULLIN	454..593	CDD:214545
		Cullin_Nedd8	701..765	CDD:214883
AT4G12100	NP_192947.1	Cullin	82..>412	CDD:279260	80/343 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5647
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1040292at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820