Protein Alignment Cul1 and AT1G43140

DIOPT Version :10

• Sequence 1: NP_523655.1
• Gene: Cul1 / 35742
• FlyBaseID: FBgn0015509
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_175007.2
• Gene: AT1G43140 / 3767291
• AraportID: AT1G43140
• Length: 721
• Species: Arabidopsis thaliana
• Alignment Length: 785
• Identity: 216/785 - (27%)
• Similarity: 380/785 - (48%)
• Gaps: 96/785 - (12%)

  Fly    11 QKLVNLDDIWSELVEGI---MQVFE--HEKSLTRSQYMRFYTHVYDYCTSVSAAPSGRSSGKTGG 70
            ::|:.|::.||.:..|:   .::.|  .|......||:..||.:||.|  :...|:..|
plant    12 KELILLEEGWSVMKTGVAKLQRILEDLSEPPFDPGQYINLYTIIYDMC--LQQPPNDYS------ 68

  Fly    71 AQLVGKKLYDRLEQFLKSYLSE-LLTKFKAISGEEVLLSRYTKQWKSYQFSSTVLDGICNYLNRN 134
                 ::||::....:..|..| :|...:...| |.:|....|:|.:::.....|...|.||:|.
plant    69 -----QELYNKYRGVVDHYNKETVLPSMRERHG-EYMLRELVKRWANHKILVRWLSRFCFYLDRF 127

  Fly   135 WVKRECEEGQKGIYKIYRLALVAWKGHLFQVLNEPVTKAVLKSIEEERQGKLINRSLVRDVIECY 199
            :|.|      :|:..:..:...::...::|.:.......:|..|.:||:|:.|:|:||::||:.|
plant   128 YVAR------RGLPTLNDVGFTSFHDLVYQEIQSEAKDVLLALIHKEREGEQIDRTLVKNVIDVY 186

  Fly   200 VELSFNEEDTDAEQQKLSVYKQNFENKFIADTSAFYEKESDAFLSTNTVTEYLKHVENRLEEETQ 264
            ......:         :.:|:::||:..:.||:::|.:::..:...::..:|:...|..|:.|.:
plant   187 CGNGVGQ---------MVIYEEDFESFLLQDTASYYSRKASRWSQEDSCPDYMLKAEECLKLEKE 242

  Fly   265 RVRGFNSKNGLSYLHETTADVLKSTCEE---VLIEKHL-KIFHTEFQNLLNADRNDDLKRMYSLV 325
            ||        .:|||.||...|....:.   |::.|.| :..|:....||..|:..||.|||.|.
plant   243 RV--------TNYLHSTTEPKLVEKVQNELLVVVAKQLIENEHSGCLALLRDDKMGDLSRMYRLY 299

  Fly   326 ALSSKNLTDLKSILENHILHQGTEAI---AKCCTTDAANDPKTYVQTILDVHKKYNALVLTAFNN 387
            .|..:.|..:..:.:.|:..:|...|   |...|...|:..:..|:..:::|.||...|...|..
plant   300 RLIPQGLEPIADLFKQHVTAEGNALIKQAADAATNQDASASQVLVRKEIELHDKYMVYVDECFQK 364

  Fly   388 DNGFVAALDKACGKFINSNVVTIANSASKSPELLAKYCDLLLKK--SSKNPEDKELEDNLNQVMV 450
            .:.|...|.:|...|.|..|     :.:.|.|:||.|||.:||.  .|:...|:..|..|.:|:.
plant   365 HSLFHKLLKEAFEVFCNKTV-----AGASSAEILATYCDNILKTRGGSEKLSDEATEITLEKVVN 424

  Fly   451 VFKYIEDKDVFQKYYSKMLAKRLVNHTSASDDAEAMMISKLKQTCGYEYTVKLQRMFQDIGVSKD 515
            :..||.|||:|.::|.|..|:||:...|.                       :.:...||.::::
plant   425 LLVYISDKDLFAEFYRKKQARRLLFDRSG-----------------------IMKEVTDITLARE 466

  Fly   516 LNSYFKQYLAEKNLT--MEIDFGIEVLSSGSWPFQLSNNFLLPSELERSVRQFNEFYAARHSGRK 578
            |.:.|..||: .|:|  :.|||.:.||::|.||...:.:..||:|:...|..|..||..:.:.|:
plant   467 LQTNFVDYLS-ANMTTKLGIDFTVTVLTTGFWPSYKTTDLNLPTEMVNCVEAFKVFYGTKTNSRR 530

  Fly   579 LNWLYQMCKGELIMNVNRNNSSTYTLQASTFQMSVLLQFN--DQLSFTVQQLQDNTQTQQENLIQ 641
            |:|:|.:....::   .:....|..|..||:|.:|||.||  ::||:|  ::.:......|:|::
plant   531 LSWIYSLGTCHIL---GKFEKKTMELVVSTYQAAVLLLFNNAERLSYT--EISEQLNLSHEDLVR 590

  Fly   642 VLQIL--LKAKVLTSSDNENSLTPESTVELFLDYKNKKRRININQPLKTELKVEQETVHKHIEED 704
            :|..|  ||.|:|.......:::...|.|....:.:|.|:|.:..|...|.|    .|.:.:::|
plant   591 LLHSLSCLKYKILIKEPMSRTISKTDTFEFNSKFTDKMRKIRVPLPPMDERK----KVVEDVDKD 651

  Fly   705 RKLLIQAAIVRIMKMRKRLNHTNLISEVLNQLSTRFKPKVPVIKKCIDILIEKEYLERMEGHKDT 769
            |:..|.||:|||||.||.|.|..|:||.:..||..|||.:.:|||.|:.||.::||||...:.:|
plant   652 RRYAIDAALVRIMKSRKVLAHQQLVSECVEHLSKMFKPDIKMIKKRIEDLINRDYLERDTENANT 716

  Fly   770 YSYLA 774
            :.|:|
plant   717 FKYVA 721

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cul1	NP_523655.1	Cullin	20..673	CDD:459983	172/673 (26%)
		Cullin_Nedd8	704..765	CDD:463146	32/60 (53%)
AT1G43140	NP_175007.2	Cullin	21..624	CDD:459983	172/673 (26%)
		Cullin_Nedd8	651..713	CDD:463146	32/61 (52%)