DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12159 and FAM174B

DIOPT Version :9

Sequence 1:	NP_610330.1	Gene:	CG12159 / 35741	FlyBaseID:	FBgn0033232	Length:	202	Species:	Drosophila melanogaster
Sequence 2:	NP_997329.2	Gene:	FAM174B / 400451	HGNCID:	34339	Length:	159	Species:	Homo sapiens

Alignment Length:	175	Identity:	41/175 - (23%)
Similarity:	69/175 - (39%)	Gaps:	46/175 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 VVIAEQSAPAAEV----EAKKPVVKKSQAENPPAGPKDSMVVVDDGGP-------APVAPGASVA 87
            :::|..:||||..    ....|..:..:...||.||          ||       :..|.|:..:
Human    14 LLLALLAAPAARASRAESVSAPWPEPERESRPPPGP----------GPGNTTRFGSGAAGGSGSS 68

  Fly    88 TQVSPGDAKAPEMVQPPGGLPVDDVHVERSPMSPDVDFPGQAVVYILVGITSTAILLLIMRVYR- 151
            :..|.|||....:......||.                 .:|.|.:....|:..|..|::||:|
Human    69 SSNSSGDALVTRISILLRDLPT-----------------LKAAVIVAFAFTTLLIACLLLRVFRS 116

  Fly   152 -LRLSRAERKYGVQGDRANQ-ELTPLPMAIEDVNSDEEDHTLFEV 194
             .||.:. |||.:....|.: |:.||    .:.:.::||.|:|::
Human   117 GKRLKKT-RKYDIITTPAERVEMAPL----NEEDDEDEDSTVFDI 156

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12159	NP_610330.1	DUF1180	40..195	CDD:284165	40/169 (24%)
FAM174B	NP_997329.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	30..74		10/53 (19%)
FAM174B	NP_997329.2	DUF1180	<75..158	CDD:284165	25/104 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR28607
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	2	2.060