Protein Alignment Dgk and PRKCB

DIOPT Version :9

• Sequence 1: NP_724619.2
• Gene: Dgk / 35738
• FlyBaseID: FBgn0085390
• Length: 1230
• Species: Drosophila melanogaster
• Sequence 2: NP_002729.2
• Gene: PRKCB / 5579
• HGNCID: 9395
• Length: 673
• Species: Homo sapiens
• Alignment Length: 397
• Identity: 81/397 - (20%)
• Similarity: 134/397 - (33%)
• Gaps: 126/397 - (31%)

  Fly   410 HVWRLKHFSKPAYCNLCLNMLVGLGKKGLCCVLCKYTVHERCVQHAPASCITTYVKSKKPKCGGD 474
            |.:..:.|.:|.:|:.|.:.:.|.||:|..|.:|.:.||:||.:....||...   .|.|.....
Human    37 HKFTARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPGA---DKGPASDDP 98

  Fly   475 LLHHWVEGNCYGR---CSKCRKRIKAYHGI--TGLTCRWCHMMLHNRCASSVKKECTLGEYSE-- 532
            ...|..:.:.|..   |..|...:   :|:  .|:.|..|.|.:|.||..:|...|.. :::|
Human    99 RSKHKFKIHTYSSPTFCDHCGSLL---YGLIHQGMKCDTCMMNVHKRCVMNVPSLCGT-DHTERR 159

  Fly   533 --LIVPPTAICPAVLDRQRSVNQAHKATHFQITPPDELSCP---LLVFVNPKSGGRQGDRILRKF 592
              :.:      .|.:||...:.....|.:.....|:.||.|   |.:..:|||..:|..:.::
Human   160 GRIYI------QAHIDRDVLIVLVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIK-- 216

  Fly   593 QYMLNPRQVYDLSKGGPKEGLTLFKDLPRFRVICCGGDGTVGWVLEAMDSIELASQPAIGVIPLG 657
             ..|||.                :.:..||::
Human   217 -CSLNPE----------------WNETFRFQL--------------------------------- 231

  Fly   658 TGNDLARCLRWGGGYEGENIPKLMDKFRRASTVMLDRWSIEVTNTPHSDDMRPKVTLHSNMQKVI 722
                                 |..||.||.|..:.| |.:    |..:|.|.......|.:||..
Human   232 ---------------------KESDKDRRLSVEIWD-WDL----TSRNDFMGSLSFGISELQKAS 270

  Fly   723 E------LSQ------SVVVDKSLMERFEEIQRQSKQVATSMGTAASSTSIMMASKTETEMETMA 775
            .      |||      :|.|.....|..||::::.::...|.||           |...|..|..
Human   271 VDGWFKLLSQEEGEYFNVPVPPEGSEANEELRQKFERAKISQGT-----------KVPEEKTTNT 324

  Fly   776 TMEFGSS 782
            ..:|.::
Human   325 VSKFDNN 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dgk	NP_724619.2	DAG_kinase_N	9..313	CDD:291199
		EFh	317..386	CDD:238008
		EF-hand_7	318..382	CDD:290234
		C1	410..459	CDD:237996	15/48 (31%)
		C1_1	477..528	CDD:278556	14/55 (25%)
		DAGKc	573..694	CDD:214487	15/120 (13%)
		DAGKa	1003..1194	CDD:214486
PRKCB	NP_002729.2	C1_cPKC_rpt1	35..92	CDD:410383	17/57 (30%)
		C1_cPKC_rpt2	102..155	CDD:410386	14/56 (25%)
		C2_PKC_alpha_gamma	159..289	CDD:175992	35/213 (16%)
		STKc_cPKC_beta	341..663	CDD:270767

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910