Protein Alignment Dgk and dgki

DIOPT Version :10

• Sequence 1: NP_724619.2
• Gene: Dgk / 35738
• FlyBaseID: FBgn0085390
• Length: 1230
• Species: Drosophila melanogaster
• Sequence 2: XP_031754398.1
• Gene: dgki / 100491416
• XenbaseID: XB-GENE-996218
• Length: 1095
• Species: Xenopus tropicalis
• Alignment Length: 414
• Identity: 85/414 - (20%)
• Similarity: 141/414 - (34%)
• Gaps: 131/414 - (31%)

  Fly    82 PSLTVCFQK---RLNEAARDQLIAQVDPELAERYGEFLDTLLESDIENVGH--LAEFDEF----- 136
            |.|..||.:   .:.:...|. ..||.||           |.|::...:|.  |||.|..
 Frog   130 PELKECFVELGLNIGQLGIDD-STQVPPE-----------LFENEHVRIGQKVLAEQDSAAAQQY 182

  Fly   137 --EGT------DLRQLLNELTDRPNAVVTMEGDL------HGTLVRSLTEMGICYTFNTAIGRYL 187
              :|:      :|..|:..::.:|..|:..| .|      |..||.||....:..|        .
 Frog   183 IRQGSPTALRAELWALILNISSQPEDVLYYE-QLKTNVIQHDLLVDSLIYKDVKLT--------A 238

  Fly   188 SIDPY--APDEKLYEVSLFGGMFQVCRRLLVKSIFGKIFFHSPYEMPTIRKSLLIERGFFTFTKM 250
            |.|.|  ..::.||:|            ||..|....:..|..:...:..||.:  ||
 Frog   239 SNDDYYFVFEDYLYQV------------LLCFSRDTSVLSHFAFNSASPPKSYI--RG------- 282

  Fly   251 DFNALAITSVPALKSLSIKQRKCRFPHESNLKF--FPEYYSYGLCLL---ECKFYLFLKHCDCIP 310
                          .|.:::....:|....:.|  |..|.: .||.|   ..|.|...:.. .:.
 Frog   283 --------------KLGLEEYAVFYPPNGVIPFHGFSMYVA-PLCFLYHEPSKLYQIFREM-YVR 331

  Fly   311 YFYQI----SDPSKYCKLSQLACVELYQSYISFLTADELREIFGACNCLKNCDDVTFTLQHYGST 371
            :|:::    |.||....|. |....|.|:|:..|.. .|||| ||
 Frog   332 FFFRLHSISSHPSGIVSLC-LLFETLLQTYLPQLFY-HLREI-GA-------------------- 373

  Fly   372 FWFNDPV---IKWSIRIPKIRYSRRIIFDFIDAMGELKVKRNEVSTGSIL-EFFFGFSIITLVEL 432
                .|:   .||.:|    .:|..:..|.:..:.:..:..|.:...::| ...|.|..:.|:|:
 Frog   374 ----QPLRISFKWMVR----AFSGYLATDQLLLLWDRILGYNSLEILAVLAAAVFAFRAVNLMEV 430

  Fly   433 AYFSMRNLI---LSCLRIKMITRI 453
            ...:....:   ||.|::..:.:|
 Frog   431 TSLAAAEAVLADLSTLKVMPLLQI 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dgk	NP_724619.2	DAG_kinase_N	9..117	CDD:464196	9/37 (24%)
		EFh	317..386	CDD:238008	18/71 (25%)
		C1_DGKbeta_rpt1	403..468	CDD:410395	10/55 (18%)
		C1_DGK_typeI_like_rpt2	477..528	CDD:410401
		DAGKc	573..694	CDD:214487
		DAGKa	1003..1194	CDD:214486
dgki	XP_031754398.1	C1_DGKiota_rpt1	175..247	CDD:410400	17/80 (21%)
		C1_DGKiota_rpt2	267..341	CDD:410446	16/98 (16%)
		DAGKc	395..516	CDD:214487	10/60 (17%)
		DAGKa	543..700	CDD:214486
		ANKYR	<959..1094	CDD:440430
		ANK repeat	959..986	CDD:293786
		ANK repeat	991..1021	CDD:293786
		ANK repeat	1023..1055	CDD:293786