Protein Alignment phr and PHR1

DIOPT Version :10

• Sequence 1: NP_523653.2
• Gene: phr / 35735
• FlyBaseID: FBgn0003082
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_015031.1
• Gene: PHR1 / 854568
• SGDID: S000005913
• Length: 565
• Species: Saccharomyces cerevisiae
• Alignment Length: 581
• Identity: 115/581 - (19%)
• Similarity: 200/581 - (34%)
• Gaps: 173/581 - (29%)

  Fly    21 MKRTKAQKAGPSKKAAKNEKASSEPKSDQESSDEEASTSKALLVSKPDYQNFEQF--LTHLEHQR 83
            ||||..        ::.|..||...:.|.|                   .:|||:  |....:.|
Yeast     1 MKRTVI--------SSSNAYASKRSRLDIE-------------------HDFEQYHSLNKKYYPR 38

  Fly    84 VCTAANIQEFS--FRKKRVRVLSKTEDVKESS---LGGVVYWMSRDGRVQDNWAL-----LFAQR 138
            ..|.....:|:  .|.|.:.::.|.:..:::|   :..|::|...|.|:.||..|     ||.|.
Yeast    39 PITRTGANQFNNKSRAKPMEIVEKLQKKQKTSFENVSTVMHWFRNDLRLYDNVGLYKSVALFQQL 103

  Fly   139 LALKLELPLTVVFCLVPKFLNATIR---HYKFMMGGLQEVEQQCRALDIP-----FHLLMGSAVE 195
            .....:..|..|:.:......|.:.   ...|:||.|:.::|....|.||     || ...|.:.
Yeast   104 RQKNAKAKLYAVYVINEDDWRAHMDSGWKLMFIMGALKNLQQSLAELHIPLLLWEFH-TPKSTLS 167

  Fly   196 KLPQFVK---------SKDIGAVVCDFAPLRLPRQWVEDVGKALPKSVPLVQVDAHN-------- 243
            ...:||:         |...|.::         ...:|.....|.:.:.|::.:.|.
Yeast   168 NSKEFVEFFKEKCMNVSSGTGTII---------TANIEYQTDELYRDIRLLENEDHRLQLKYYHD 223

  Fly   244 ---VVPLWVASDKQEYAARTIRNKINSKLGEYLSVFPP--------VVRHPHGTG--C------- 288
               |.|..:.:|:                |...|||.|        |..:...|.  |
Yeast   224 SCIVAPGLITTDR----------------GTNYSVFTPWYKKWVLYVNNYKKSTSEICHLHIIEP 272

  Fly   289 -KNVNTVDWSAAYASLQCD--MEVDEVQWAKP--GYKAACQQLYEFCSRRLRHFNDKRNDPTADA 348
             |...|.:......||..:  ..:.:.:|..|  ..:||..:|.:|...:...:|::::......
Yeast   273 LKYNETFELKPFQYSLPDEFLQYIPKSKWCLPDVSEEAALSRLKDFLGTKSSKYNNEKDMLYLGG 337

  Fly   349 LSGLSPWLHFGHISAQRCALEVQRFRGQHKASADAFCEEAIVRRELADN---------------- 397
            .||||.::..|.||.:  .:..|.|:.         |...|:.:.|.||
Yeast   338 TSGLSVYITTGRISTR--LIVNQAFQS---------CNGQIMSKALKDNSSTQNFIKEVAWRDFY 391

  Fly   398 -FCFYNEHYDSLKGLSSWAYQTLDAHRKDKRDPCYSLEELEKSLTYDDLWNSAQLQLVREGKMHG 461
             .|..|..|.|: |: .:...|||.  |.:.:| .:.|:.....|...:.::...:|:..|.::.
Yeast   392 RHCMCNWPYTSM-GM-PYRLDTLDI--KWENNP-VAFEKWCTGNTGIPIVDAIMRKLLYTGYINN 451

  Fly   462 FLRM----YWAKKIL-EWTATPEHALEYAILLNDKYSLDGRDPNGYVGCMWSIGGVHDMGW 517
            ..||    :.:|.:| :|.......:        |:.:|| |.:..||           ||
Yeast   452 RSRMITASFLSKNLLIDWRWGERWFM--------KHLIDG-DSSSNVG-----------GW 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phr	NP_523653.2	phr2	93..547	CDD:129679	100/507 (20%)
PHR1	NP_015031.1	PhrB	75..564	CDD:440184	95/480 (20%)