Protein Alignment puml and LDH1

DIOPT Version :9

• Sequence 1: NP_001286169.1
• Gene: puml / 35733
• FlyBaseID: FBgn0033226
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_009763.2
• Gene: LDH1 / 852503
• SGDID: S000000408
• Length: 375
• Species: Saccharomyces cerevisiae
• Alignment Length: 422
• Identity: 80/422 - (18%)
• Similarity: 147/422 - (34%)
• Gaps: 148/422 - (35%)

  Fly    57 WLCNWTSSSPTMLRAVEK-----KILSYVKLPYRGFFVDIG---PAVGEADKIWTISMNTESKEV 113
            |.|. ..|..|:...|:.     .:::|::.|.    ||:.   ..:.|.::.:.:.::..:..:
Yeast    13 WSCE-PLSGKTLEEIVQNAENAADLVAYIRKPE----VDLDFRLKFIAEHEEFFNVQLSDRNSRI 72

  Fly   114 ---------------PLVLLHGLGAGIALWVMNLDAF--------AKGRPVYAMDILGFGRSSR- 154
                           ..|.:.|| ||      ||:.|        :..:....:|:.|||.||.
Yeast    73 RTCHNLSDKGIRGDTVFVFVPGL-AG------NLEQFEPLLELVDSDQKAFLTLDLPGFGHSSEW 130

  Fly   155 ---PLFAK----DALVCEKQFVKSVEEWRREMNIND---------MILLGHSMGGFIASSYALSH 203
               |:...    ..|||:     .:.:|...:..||         ::|:|||||.|:|.
Yeast   131 SDYPMLKVVELIFVLVCD-----VLRKWSTAVPNNDNVNPFNGHKIVLVGHSMGCFLAC------ 184

  Fly   204 PERVKHLILADPWGFPEKPSDSTNGKTIPLWVRAIARVLTP----LNPL--------WALRAAGP 256
                 ||       :.:..:|:...:|:.|        |||    :..|        |||  .|.
Yeast   185 -----HL-------YEQHMADTKAVQTLVL--------LTPPKAHIEQLSKDKHIIQWAL--YGV 227

  Fly   257 FG-QWV--VQKTRPDIMRKFQSTIEEDINLLPQYIHQ----------------CNAQNPSGESAF 302
            |. .|:  |.:.:.|.::..||      :.:.||.:|                .|..|.|.....
Yeast   228 FKLPWLFDVYRNKFDQVKGLQS------SGIKQYFYQQGDDVKLKYRKFWQFKNNISNKSRTIIG 286

  Fly   303 HTM-MQSFGWAKHPMIHRIKDVRSDI--------PITFIYGSRSWIDSSSGEKIKSQRGSNMVDI 358
            :.: .::..|.|...:....|::..|        ||..|.....:..:.:.|.::.        :
Yeast   287 YLLGWETVDWVKFNGVLTQTDMKQKIIIFGAEKDPIAPIENLEFYKQTINKECLRK--------V 343

  Fly   359 KIVTGAGHHVYADKPD-VFNRYVNETCDMYKV 389
            .|:....|::..|:|: |...:..|..|..|:
Yeast   344 IILPDCSHNLCFDRPELVCENFQREVIDNSKL 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
puml	NP_001286169.1	MhpC	114..382	CDD:223669	67/333 (20%)
		Abhydrolase_5	114..>226	CDD:289465	32/136 (24%)
LDH1	NP_009763.2	EstA	4..375	CDD:224001	79/420 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341689
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930