Protein Alignment puml and BPHL

DIOPT Version :9

• Sequence 1: NP_001286169.1
• Gene: puml / 35733
• FlyBaseID: FBgn0033226
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_004323.2
• Gene: BPHL / 670
• HGNCID: 1094
• Length: 291
• Species: Homo sapiens
• Alignment Length: 350
• Identity: 72/350 - (20%)
• Similarity: 124/350 - (35%)
• Gaps: 110/350 - (31%)

  Fly    69 LRAVEKKILSYVKLPYRGFFVDIGPAVGEADKIWTISMN--------TESKEVPLVLLHG-LGAG 124
            ||.:...:...:.:|..|.....|.:|..|    .:::|        |...:..::||.| ||:|
Human    13 LRLLLSALKPGIHVPRAGPAAAFGTSVTSA----KVAVNGVQLHYQQTGEGDHAVLLLPGMLGSG 73

  Fly   125 IA-----LWVMNLDAFAKGRPVYAMDILGFGRSSRP-------LFAKDALVCEKQFVKSVEEWRR 177
            ..     |..:|...|.    |.|.|..|:|.|..|       .|.:||        |...:..:
Human    74 ETDFGPQLKNLNKKLFT----VVAWDPRGYGHSRPPDRDFPADFFERDA--------KDAVDLMK 126

  Fly   178 EMNINDMILLGHSMGGFIASSYALSHPERVKHLILADPWGFPEKPSDSTNGKTIPLWVRAIARVL 242
            .:....:.|||.|.||..|...|..:|..:..:::   ||.....:|..:  .|...:|.:::
Human   127 ALKFKKVSLLGWSDGGITALIAAAKYPSYIHKMVI---WGANAYVTDEDS--MIYEGIRDVSK-- 184

  Fly   243 TPLNPLWALRAAGP----FG---------QWVVQKTRPDIMRKFQSTIEEDI--NLLPQYIHQCN 292
                  |:.|...|    :|         :||      |.:|:|:...:.:|  :|||:.  ||.
Human   185 ------WSERTRKPLEALYGYDYFARTCEKWV------DGIRQFKHLPDGNICRHLLPRV--QCP 235

  Fly   293 AQNPSGESAFHTMMQSFGWAKHPMIHRIKDVRSDIPITFIYGSRSWIDSSSGEKIKSQRGSNMVD 357
            |....||             |.|::.|.   .:|.....:.|||
Human   236 ALIVHGE-------------KDPLVPRF---HADFIHKHVKGSR--------------------- 263

  Fly   358 IKIVTGAGHHVYADKPDVFNRYVNE 382
            :.::....|:::....|.||:...:
Human   264 LHLMPEGKHNLHLRFADEFNKLAED 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
puml	NP_001286169.1	MhpC	114..382	CDD:223669	63/295 (21%)
		Abhydrolase_5	114..>226	CDD:289465	32/124 (26%)
BPHL	NP_004323.2	MhpC	44..291	CDD:223669	65/314 (21%)
		Abhydrolase	58..259	CDD:304388	56/249 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910