DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment puml and abhd4

DIOPT Version :9

Sequence 1:	NP_001286169.1	Gene:	puml / 35733	FlyBaseID:	FBgn0033226	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	XP_005163656.1	Gene:	abhd4 / 550276	ZFINID:	ZDB-GENE-050417-83	Length:	372	Species:	Danio rerio

Alignment Length:	349	Identity:	154/349 - (44%)
Similarity:	220/349 - (63%)	Gaps:	24/349 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 WKWLCNWTSSSPTMLRAVEKKILSYVKLPYRGFFVDIGPAVGEADKIWTISMNT--------ESK 111
            |.|..:|..:|.::|::.|.|||:.::......||    .:....:|||:.:..        ::.
Zfish    27 WSWWPSWRPTSMSLLKSAEAKILACIRNEVWSRFV----TLPNQTRIWTLKVTNKTTRKQKEQAA 87

  Fly   112 EVPLVLLHGLGAGIALWVMNLDAFAKGRPVYAMDILGFGRSSRPLFAKDALVCEKQFVKSVEEWR 176
            :.|||::||.|.|:.||:.||||.::.|||||.|:|||||||||.|..||.:.|:|||.|:|:||
Zfish    88 QTPLVMVHGFGGGVGLWIRNLDALSRSRPVYAFDLLGFGRSSRPSFPADASLAEEQFVSSIEQWR 152

  Fly   177 REMNINDMILLGHSMGGFIASSYALSHPERVKHLILADPWGFPEKPSDSTNG--------KTI-- 231
            ..|.:..|||||||:||::|:||.:.:||||.||||.|||||||:|.....|        |.:
Zfish   153 ESMGLERMILLGHSLGGYLATSYTIQYPERVSHLILVDPWGFPERPQPQVQGSAGQGSEVKRVGP 217

  Fly   232 PLWVRAIARVLTPLNPLWALRAAGPFGQWVVQKTRPDIMRKFQSTIEEDINLLPQYIHQCNAQNP 296
            |.||:|:|.|.:..|||..:|||||:|..:|.:.|||..|||:...::|  .:.|||:.||||||
Zfish   218 PRWVKALASVFSFFNPLAVIRAAGPWGPGLVNRFRPDFKRKFEDLFDDD--TMTQYIYHCNAQNP 280

  Fly   297 SGESAFHTMMQSFGWAKHPMIHRIKDVRSDIPITFIYGSRSWIDSSSGEKIKSQRGSNMVDIKIV 361
            |||..|..|.:|.||||.||:.|:..:...:|::.:|||.||:|||:|..:...||.:...:.::
Zfish   281 SGEVGFKAMCESLGWAKRPMVQRVHLLPPLMPVSLLYGSLSWVDSSTGNTVAQIRGKSPTSVTLI 345

  Fly   362 TGAGHHVYADKPDVFNRYVNETCD 385
            ..|.||||||:|:.|||.|...|:
Zfish   346 EDASHHVYADQPEEFNRVVENICN 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
puml	NP_001286169.1	MhpC	114..382	CDD:223669	139/277 (50%)
puml	NP_001286169.1	Abhydrolase_5	114..>226	CDD:289465	68/111 (61%)
abhd4	XP_005163656.1	MhpC	89..366	CDD:223669	139/278 (50%)
abhd4	XP_005163656.1	Abhydrolase_5	90..225	CDD:289465	74/134 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580889
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H56937
Inparanoid	1	1.050	325	1.000	Inparanoid score	I2462
OMA	1	1.010	-	-		QHG57834
OrthoDB	1	1.010	-	-		D1555935at2759
OrthoFinder	1	1.000	-	-		FOG0001034
OrthoInspector	1	1.000	-	-		oto40963
orthoMCL	1	0.900	-	-		OOG6_101137
Panther	1	1.100	-	-	LDO	PTHR42886
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R207
SonicParanoid	1	1.000	-	-		X562
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.940