DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment puml and abhd4

DIOPT Version :9

Sequence 1:	NP_001286169.1	Gene:	puml / 35733	FlyBaseID:	FBgn0033226	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	NP_001017287.1	Gene:	abhd4 / 550041	XenbaseID:	XB-GENE-921768	Length:	342	Species:	Xenopus tropicalis

Alignment Length:	344	Identity:	172/344 - (50%)
Similarity:	240/344 - (69%)	Gaps:	9/344 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 DLEDPRNNRFFLWKWLCNWTSSSPTMLRAVEKKILSYVKLPYRGFFVDIGPAVGEADKIWTISMN 107
            :||:  :|:.:|..|:.:|..:|.:.|:|||.:||..:|..:...:|    ::.:.:||||::::
Frog     4 ELEE--HNQNWLTGWIPSWCPTSMSKLKAVESRILQCIKNKFSAQYV----SLPDQNKIWTLTVS 62

  Fly   108 TE-SKEVPLVLLHGLGAGIALWVMNLDAFAKGRPVYAMDILGFGRSSRPLFAKDALVCEKQFVKS 171
            .| .|:.|||::||.|.||.||:.|||..:..|.::|.|:|||||||||.|..|....|:|||.|
Frog    63 PELQKKTPLVMVHGFGGGIGLWIQNLDHLSSSRTLHAFDLLGFGRSSRPNFPSDPEGAEEQFVSS 127

  Fly   172 VEEWRREMNINDMILLGHSMGGFIASSYALSHPERVKHLILADPWGFPEKPSDSTNGKTIPLWVR 236
            :|:||.:|.|.:|||||||:|||:|:||::..|||||||||.||||||..|:|.:..::.|.||:
Frog   128 IEQWREQMGIRNMILLGHSLGGFLAASYSIKFPERVKHLILVDPWGFPTMPTDPSEIRSPPTWVK 192

  Fly   237 AIARVLTPLNPLWALRAAGPFGQWVVQKTRPDIMRKFQSTIEEDINLLPQYIHQCNAQNPSGESA 301
            |:|.||...|||..:|||||:|..:||:.|||:.||||...|:|  .:.:||:.||||.||||||
Frog   193 ALAAVLGRSNPLAVVRAAGPWGPGLVQRFRPDLKRKFQEYFEDD--TIMEYIYHCNAQTPSGESA 255

  Fly   302 FHTMMQSFGWAKHPMIHRIKDVRSDIPITFIYGSRSWIDSSSGEKIKSQRGSNMVDIKIVTGAGH 366
            |.|||:.|||||.||:.||..:..|:|||||||:.:|||.|:||::|.:|..:.|....:.||.|
Frog   256 FKTMMERFGWAKRPMMSRINQIPKDLPITFIYGAETWIDRSTGERVKEERSDSFVKTLAIKGASH 320

  Fly   367 HVYADKPDVFNRYVNETCD 385
            |||||:|..||..|.|.||
Frog   321 HVYADQPGTFNAVVEEICD 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
puml	NP_001286169.1	MhpC	114..382	CDD:223669	148/267 (55%)
puml	NP_001286169.1	Abhydrolase_5	114..>226	CDD:289465	67/111 (60%)
abhd4	NP_001017287.1	Abhydrolase	54..>169	CDD:304388	64/114 (56%)
		MhpC	68..336	CDD:223669	148/269 (55%)
		Abhydrolase	<141..211	CDD:304388	41/69 (59%)
		DHR2_DOCK	<230..>338	CDD:297424	58/109 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H56937
Inparanoid	1	1.050	329	1.000	Inparanoid score	I2409
OMA	1	1.010	-	-		QHG57834
OrthoDB	1	1.010	-	-		D1555935at2759
OrthoFinder	1	1.000	-	-		FOG0001034
OrthoInspector	1	1.000	-	-		otm49431
Panther	1	1.100	-	-	LDO	PTHR42886
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X562
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	11.080