DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment puml and ephx2

DIOPT Version :9

Sequence 1:	NP_001286169.1	Gene:	puml / 35733	FlyBaseID:	FBgn0033226	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	NP_001008642.1	Gene:	ephx2 / 494099	ZFINID:	ZDB-GENE-041212-70	Length:	557	Species:	Danio rerio

Alignment Length:	214	Identity:	50/214 - (23%)
Similarity:	81/214 - (37%)	Gaps:	73/214 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 FVDIGPAVGEADKIWTISMNTESKEVPLVLLHGLGAGIALWVMNLDAFA-KGRPVYAMDILGFGR 151
            :|:|.|.|    ||..:.|....   |::|.||.......|...:.|.| .|..|.|.|:.|:|.
Zfish   237 YVNIKPGV----KIHYVEMGDGP---PVLLCHGFPESWFSWRYQIPALADAGFRVLAPDMKGYGG 294

  Fly   152 SSRPLFAKDALVCEKQFVKSVEEWRREMNINDMI------------LLGHSMGGFIASSYALSHP 204
            |:.|              ..:||:.:|..:.|::            |:||..||.:..:.|..||
Zfish   295 STAP--------------PDIEEYSQEQIMLDLVTFLDKMAIAQVTLVGHDWGGVLVWNMAQFHP 345

  Fly   205 ERVKHLILADPWGFPEKPSDSTNGKTIPLWVRAIARVLTPL-------NPLWALRAAGPFGQWVV 262
            ||                            |||:|.:.|||       ||:..|.|. |...:.:
Zfish   346 ER----------------------------VRAVASLNTPLFPVDPNTNPMEKLMAI-PIFDYQI 381

  Fly   263 QKTRPDIMRKFQSTIEEDI 281
            ...:|.:.   ::.:|:::
Zfish   382 YFQKPGVA---EAELEKNL 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
puml	NP_001286169.1	MhpC	114..382	CDD:223669	43/188 (23%)
puml	NP_001286169.1	Abhydrolase_5	114..>226	CDD:289465	29/124 (23%)
ephx2	NP_001008642.1	HAD-1A3-hyp	3..217	CDD:274054
		HAD_like	<155..203	CDD:304363
		Abhydrolase	237..>358	CDD:304388	41/169 (24%)
		Abhydrolase_1	255..531	CDD:278959	43/192 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910