DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment puml and Y73C8B.2

DIOPT Version :9

Sequence 1:	NP_001286169.1	Gene:	puml / 35733	FlyBaseID:	FBgn0033226	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	NP_001379784.1	Gene:	Y73C8B.2 / 178757	WormBaseID:	WBGene00022259	Length:	308	Species:	Caenorhabditis elegans

Alignment Length:	222	Identity:	39/222 - (17%)
Similarity:	69/222 - (31%)	Gaps:	76/222 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   265 TRPDIMR---KFQSTIEEDINLLPQYIHQCNAQNPSGE-SAFHTMMQSFGWAKHPMIHRIKDVRS 325
            :.|.:::   |||:..|:.:.|...|.....:.:|.|. .|||....|     |.....|:....
Worm    10 SEPKLLKKLVKFQAENEQFVELEAVYEDSITSGSPFGTVVAFHGSPGS-----HNDFKYIRSKLD 69

  Fly   326 DIPITFI---YGSRSWIDSSSGEKIKSQRGSNM---------VDIKIV----------------- 361
            |:.|.||   |...|......|::..:....|.         :|.||:
Worm    70 DLNIRFIGVNYPGFSNTPEYEGQQHANPERQNFSNALLDELKIDGKIIYMGHSRGCENALQTAVG 134

  Fly   362 -----------TGAGHH--------------VYADKPDVFNRYVNETCDMYKVAGGKLITPLQLI 401
                       ||..||              :|...|.....  :....:||..|.|:
Worm   135 REAHGLVLINPTGFRHHQGIRPFYRLEYLDWMYGLLPSFLGN--SMILGIYKAIGFKV------- 190

  Fly   402 RESTESDEEREPSLSTAKTVEVQPEVQ 428
                :|.||...::.:...:.::.:::
Worm   191 ----KSGEEAMCAMRSVMRMSLEDQIE 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
puml	NP_001286169.1	MhpC	114..382	CDD:223669	32/174 (18%)
puml	NP_001286169.1	Abhydrolase_5	114..>226	CDD:289465
Y73C8B.2	NP_001379784.1	DUF1057	11..307	CDD:115027	39/221 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156704
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930