Protein Alignment TTLL12 and ttll12

DIOPT Version :10

• Sequence 1: NP_610325.1
• Gene: TTLL12 / 35732
• FlyBaseID: FBgn0033225
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: XP_031754361.1
• Gene: ttll12 / 100486512
• XenbaseID: XB-GENE-6047893
• Length: 640
• Species: Xenopus tropicalis
• Alignment Length: 596
• Identity: 255/596 - (42%)
• Similarity: 363/596 - (60%)
• Gaps: 45/596 - (7%)

  Fly    40 FDAGEALQLMLI----DYDEDEQQNPAEDDDSPNPVFALG--------VAREQGIKASDPQAIYL 92
            |||||...:..:    :.||:|::...::...|||    |        |..|.|::||:|.:|:|
 Frog    58 FDAGEMFGITYVEEAEEEDEEEEELQEQEMKKPNP----GTDPRSKVIVTHEGGLRASNPNSIFL 118

  Fly    93 VDHAWTFRLNGARQQLEEYPQLAERLSAITGVDL--ELKDR--VDKILRRLWKYCHAYSIGSEGL 153
            :|||||:|::.|||||.:.|.|..|::.:.|:..  |:.|.  |:.:|:.:|||...|.: |.|
 Frog   119 IDHAWTYRVDHARQQLLQVPGLFHRMANLIGLPFHGEVPDEGMVEAVLQEMWKYNQTYQL-SHG- 181

  Fly   154 SDEERQPIWYVMDEVGSAVNHSDDPNFRLVPLLYLNTQTTYSVLFPIRDCDVGEAVTRDMVEHVA 218
            |.||:.|:||:|||.||.:.|||:|.|...||.|...|..::||:|:||.:.||.||||.. :..
 Frog   182 SAEEKVPVWYIMDEFGSQIQHSDEPTFCTAPLFYFPQQIAFTVLWPLRDLENGEEVTRDFA-YGE 245

  Fly   219 KDAPQRPALLLPWRDADLTGESFLQVEPRADYFTS--GHIPETYPKGDTVPL-PARSRCDP-LKV 279
            .|...|..||.|||..|:|.......||.|.|:.:  ....|:.|    ||: ||....|. |||
 Frog   246 PDPLIRNCLLHPWRPVDITHIGCHTPEPPASYYEAIFAENKESLP----VPITPASPTQDKVLKV 306

  Fly   280 YAEYEVVRRHLTSSEFILVNNADEADVLWLTHHFKNFEDFADRSPGKFINQFPFEYVITIKDLLS 344
            :.:.:.|...||...|...::..|||||:...|.|:::..:...|...:||||.|.::|:||.|:
 Frog   307 HTDMQQVLGGLTHPRFQFTDDEKEADVLFKFSHIKDYKALSTERPHLLLNQFPCENLLTVKDCLA 371

  Fly   345 IVGRRAAKEHHDSLTLETFPAWLPTTYNLSTEVKEFAAYYQTRAAKGLDNHWIIKPWNLARGLDT 409
            .|.|||..           |.|||.|:||.||:.:|.:|::.|..:|.|||||.|||||||||||
 Frog   372 SVSRRAGG-----------PRWLPQTFNLRTELPQFISYFKQREQRGDDNHWICKPWNLARGLDT 425

  Fly   410 HITDNIKQIVRLPATGPKIAQKYIERPVLFSRQEVEGSVKFDIRYVILLKSVKPLKAYIHRKFFL 474
            |:|.|:..|:|...:.||:..||||.||||.|.:| |.||||||||:||:||:||:.|.:..|:|
 Frog   426 HVTTNLSYIIRQRESTPKVVCKYIEDPVLFHRDDV-GLVKFDIRYVVLLRSVQPLRLYAYDVFWL 489

  Fly   475 RFANHPFTLDHFDDYEKHYTVMNYQTEAQLHHVKCDDFLTLWQEQYPDNDWSALEQQICSMLLEV 539
            ||||.||.||..|:||||:|||||....:|..|.||:|:||:::|.|:..||:::.::.....|:
 Frog   490 RFANRPFALDELDNYEKHFTVMNYTPGVELKQVHCDEFITLFEKQNPEIQWSSIQAELFKCFREL 554

  Fly   540 LQCASQADPPCGLAPCAQSRALYAADIMLRWKDDKE--KLMEPQLLEINWTPDCKRACDYYPDFF 602
            .:.|:....|.|:.....|||:||.|:||:|:.|.|  ::|:||:||:|:.|||.|||.|:|.||
 Frog   555 FEAAASKPAPYGICNYPSSRAMYAIDLMLKWETDTEGKRVMQPQILEVNFNPDCARACKYHPSFF 619

  Fly   603 NDIFRLLFLDE 613
            ||:|..|||.|
 Frog   620 NDVFSTLFLGE 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL12	NP_610325.1	CPSase_L_D2	328..613	CDD:473076	143/286 (50%)
ttll12	XP_031754361.1	TTL	345..628	CDD:397308	142/294 (48%)