DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sax and CRK42

DIOPT Version :9

Sequence 1:	NP_001246193.1	Gene:	sax / 35731	FlyBaseID:	FBgn0003317	Length:	582	Species:	Drosophila melanogaster
Sequence 2:	NP_198854.3	Gene:	CRK42 / 834036	AraportID:	AT5G40380	Length:	651	Species:	Arabidopsis thaliana

Alignment Length:	458	Identity:	106/458 - (23%)
Similarity:	175/458 - (38%)	Gaps:	146/458 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 QCWKSRTRDADGQVQESRGCSTSPDQLPMICSQNSLK-INGPSKRNTGKFVNVVCCA--GD---Y 159
            |||:|..::         .|        .:|.:.::| :.....|..|:.:|..|..  .|   |
plant   190 QCWESLGKE---------DC--------RVCLEKAVKEVKRCVSRREGRAMNTGCYLRYSDHKFY 237

  Fly   160 CNEGDFPELLPFDSNDVTVITADTSSISKMLVAVLGPFLVIALLGAVTIFFIRRSHRKRLAASRT 224
            ..:|.....:.|:...:..|...||:           |:::.||....|.         ...|:|
plant   238 NGDGHHKFHVLFNKGVIVAIVLTTSA-----------FVMLILLATYVIM---------TKVSKT 282

  Fly   225 KQDPEAY-LVN------------DELLRATSAGDSTLREYLQHSVTSGSGSGLPLLVQRTLAKQV 276
            ||:.... ||:            :.|.:||        :|..|.
plant   283 KQEKRNLGLVSRKFNNSKTKFKYETLEKAT--------DYFSHK--------------------- 318

  Fly   277 TLIECIGRGKYGEVWRGHW-HGESIAVK--IFFSRD-EESWKRETEIYSTILLRHENILGFIGSD 337
               :.:|:|..|.|:.|.. :|:::|||  :|.:|| .|.:..|..:.|.|  :|:|::..:|..
plant   319 ---KMLGQGGNGTVFLGILPNGKNVAVKRLVFNTRDWVEEFFNEVNLISGI--QHKNLVKLLGCS 378

  Fly   338 MTSRNSCTQLWLMTHYYPLGS----LFDHLNRNALSHNDMVWICLSIANGLVHLHTEIFGKQGKP 398
            :....|.    |:..|.|..|    |||......|:.:..:.|.|..|.||.:||      .|.|
plant   379 IEGPESL----LVYEYVPNKSLDQFLFDESQSKVLNWSQRLNIILGTAEGLAYLH------GGSP 433

  Fly   399 A-MAHRDLKSKNILVTSNGSCVIADFGLA----VTHSHVTGQLDLGNNPKVGTKRYMAPEVLDES 458
            . :.|||:|:.|:|:....:..|||||||    :..:|::..:       .||..|||||.:...
plant   434 VRIIHRDIKTSNVLLDDQLNPKIADFGLARCFGLDKTHLSTGI-------AGTLGYMAPEYVVRG 491

  Fly   459 IDLECFEALRRTDIYAFGLVLWEVCRRTISCGIAEEYKVP-----------FYD----VVPMDPS 508
                  :...:.|:|:||:::.|     |:||......||           .|.    |..:||.
plant   492 ------QLTEKADVYSFGVLVLE-----IACGTRINAFVPETGHLLQRVWNLYTLNRLVEALDPC 545

  Fly   509 FED 511
            .:|
plant   546 LKD 548

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sax	NP_001246193.1	Activin_recp	77..168	CDD:279413	14/72 (19%)
		TM_EGFR-like	182..218	CDD:213052	6/35 (17%)
		TGF_beta_GS	247..274	CDD:285687	2/26 (8%)
		STKc_ACVR1_ALK1	270..567	CDD:271044	73/270 (27%)
		TyrKc	276..553	CDD:197581	73/264 (28%)
CRK42	NP_198854.3	Stress-antifung	40..131	CDD:279926
		Stress-antifung	<174..232	CDD:279926	11/58 (19%)
		Pkinase_Tyr	319..588	CDD:285015	73/260 (28%)
		STKc_IRAK	321..590	CDD:270968	73/258 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910