Protein Alignment sax and bmpr1b

DIOPT Version :10

• Sequence 1: NP_001246193.1
• Gene: sax / 35731
• FlyBaseID: FBgn0003317
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_001072633.1
• Gene: bmpr1b / 780089
• XenbaseID: XB-GENE-483455
• Length: 532
• Species: Xenopus tropicalis
• Alignment Length: 591
• Identity: 244/591 - (41%)
• Similarity: 335/591 - (56%)
• Gaps: 88/591 - (14%)

  Fly     2 ESNIYLVFLLTFLLYNNARAEISDHLREDIPDLDMELSSASSAHLNGKE------LPAVPQNSVQ 60
            |.|..|...|..||..:.||.:.|         :|.|.|::..:::.::      .||.||
 Frog     6 ERNWQLHVSLIMLLSLHTRANLLD---------NMLLRSSAKLNVDSRKEDTESTAPAPPQ---- 57

  Fly    61 THPRRHIKSKRRMKRRYKCYSCEPPCRDPYEFTHTCQNAIQCWKSRTRDADGQVQESRGCSTSPD 125
                          :...|| |...|.:. .|.:||.....|:.....|..|
 Frog    58 --------------KMLACY-CHHHCPED-SFNNTCWTDGYCFTIVEEDESG------------- 93

  Fly   126 QLPMICSQNSLKING----------PSKRNTGKFVNVVCCAG-DYCNEGDFPELLPFDSNDVTVI 179
             ||::.| ..|.:.|          |.:|.     ::.||.. |:||....|.|.|....|..
 Frog    94 -LPVVTS-GCLGLEGSDFQCRDTPIPHQRR-----SIECCTDEDFCNRDLHPTLPPLKKPDFV-- 149

  Fly   180 TADTSSISKMLVAVLGPFLVIALLGAVTIFFIRRSHRKRLAASR----TKQDPEAYLVNDELLRA 240
               ..||..|  |:|....|.:::.|:.:.|....::::.|..|    .:|| |.|:...|
 Frog   150 ---DGSIHYM--ALLISVTVCSIILAIILIFCYFRYKRQEARPRYSIGIEQD-ETYIPPGE---- 204

  Fly   241 TSAGDSTLREYLQHSVTSGSGSGLPLLVQRTLAKQVTLIECIGRGKYGEVWRGHWHGESIAVKIF 305
                  :|::.::.|.:||||||||||||||:|||:.:::.||:|:|||||.|.|.||.:|||:|
 Frog   205 ------SLKDLIEQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRGEKVAVKVF 263

  Fly   306 FSRDEESWKRETEIYSTILLRHENILGFIGSDMTSRNSCTQLWLMTHYYPLGSLFDHLNRNALSH 370
            |:.:|.||.||||||.|:|:|||||||||.:|:....|.|||:|:|.|:..|||:|:|....|..
 Frog   264 FTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDT 328

  Fly   371 NDMVWICLSIANGLVHLHTEIFGKQGKPAMAHRDLKSKNILVTSNGSCVIADFGLAVTHSHVTGQ 435
            ..|:.:..|..:||.||||||||.:||||:||||||||||||..||:|.|||.||||.....|.:
 Frog   329 KAMLKLAYSTVSGLCHLHTEIFGTKGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISDTNE 393

  Fly   436 LDLGNNPKVGTKRYMAPEVLDESIDLECFEALRRTDIYAFGLVLWEVCRRTISCGIAEEYKVPFY 500
            :|:..|.:|||||||.|||||||::...|::....|:|:|||:||||.||.||.||.|||::|::
 Frog   394 VDIPPNTRVGTKRYMPPEVLDESLNRNHFQSYIMADMYSFGLILWEVARRCISGGILEEYQLPYH 458

  Fly   501 DVVPMDPSFEDMRKVVCIDNYRPSIPNRWSSDSLMTGMSKLMKECWHQNPDVRLPALRIKKTIHK 565
            ||||.|||:||||::|||..:|||.|||||||..:..|.|||.|||..||..||.|||:|||:.|
 Frog   459 DVVPSDPSYEDMREIVCIRRFRPSFPNRWSSDECLRQMGKLMTECWAHNPASRLTALRVKKTLAK 523

  Fly   566 LASADE 571
            ::.:.:
 Frog   524 MSESQD 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sax	NP_001246193.1	TFP_LU_ECD_Sax	74..166	CDD:467129	22/102 (22%)
		TM_EGFR-like	182..218	CDD:213052	8/35 (23%)
		TGF_beta_GS	247..274	CDD:462503	16/26 (62%)
		STKc_ACVR1_ALK1	270..567	CDD:271044	173/296 (58%)
bmpr1b	NP_001072633.1	TFP_LU_ECD_BMPR1B	58..143	CDD:467133	24/106 (23%)
		TGF_beta_GS	205..232	CDD:462503	16/26 (62%)
		Protein Kinases, catalytic domain	228..532	CDD:473864	173/302 (57%)