Protein Alignment sax and BMPR1B

DIOPT Version :9

• Sequence 1: NP_001246193.1
• Gene: sax / 35731
• FlyBaseID: FBgn0003317
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_001243722.1
• Gene: BMPR1B / 658
• HGNCID: 1077
• Length: 532
• Species: Homo sapiens
• Alignment Length: 599
• Identity: 242/599 - (40%)
• Similarity: 329/599 - (54%)
• Gaps: 104/599 - (17%)

  Fly     2 ESNIYLVFLLTFLLYNNARAEISDHLREDIPDLDMELSSASSAHLNGKELPAVPQNSVQTHPRRH 66
            |.|..|...|..||..:.||...|         :|.|.||...::..|:     ::...|.|
Human     6 ELNWQLHIFLLILLSMHTRANFLD---------NMLLRSAGKLNVGTKK-----EDGESTAP--- 53

  Fly    67 IKSKRRMKRRYKCYSCEPPCRDPYEFTHTCQNAIQCWKSRTRDADGQVQESRG-CSTSPDQ---- 126
              :.|....|.||:             |.|          ..|:...:..:.| |.|..::
Human    54 --TPRPKVLRCKCH-------------HHC----------PEDSVNNICSTDGYCFTMIEEDDSG 93

  Fly   127 LPMICSQNSLKING----------PSKRNTGKFVNVVCCA-GDYCNEGDFPELLPFDSNDVTVIT 180
            ||::.| ..|.:.|          |.:|.     ::.||. .:.||:...|.|.|..:.|.
Human    94 LPVVTS-GCLGLEGSDFQCRDTPIPHQRR-----SIECCTERNECNKDLHPTLPPLKNRDF---- 148

  Fly   181 ADTSSISKMLVAVLGPFLVIALLGAVTI-------------FFIRRSHRKRLAASRTKQDPEAYL 232
                        |.||....|||.:||:             |..:|...:...:...:|| |.|:
Human   149 ------------VDGPIHHRALLISVTVCSLLLVLIILFCYFRYKRQETRPRYSIGLEQD-ETYI 200

  Fly   233 VNDELLRATSAGDSTLREYLQHSVTSGSGSGLPLLVQRTLAKQVTLIECIGRGKYGEVWRGHWHG 297
            ...|          :||:.::.|.:||||||||||||||:|||:.:::.||:|:|||||.|.|.|
Human   201 PPGE----------SLRDLIEQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRG 255

  Fly   298 ESIAVKIFFSRDEESWKRETEIYSTILLRHENILGFIGSDMTSRNSCTQLWLMTHYYPLGSLFDH 362
            |.:|||:||:.:|.||.||||||.|:|:|||||||||.:|:....|.|||:|:|.|:..|||:|:
Human   256 EKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDY 320

  Fly   363 LNRNALSHNDMVWICLSIANGLVHLHTEIFGKQGKPAMAHRDLKSKNILVTSNGSCVIADFGLAV 427
            |....|....|:.:..|..:||.|||||||..|||||:||||||||||||..||:|.|||.||||
Human   321 LKSTTLDAKSMLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAV 385

  Fly   428 THSHVTGQLDLGNNPKVGTKRYMAPEVLDESIDLECFEALRRTDIYAFGLVLWEVCRRTISCGIA 492
            .....|.::|:..|.:|||||||.|||||||::...|::....|:|:|||:||||.||.:|.||.
Human   386 KFISDTNEVDIPPNTRVGTKRYMPPEVLDESLNRNHFQSYIMADMYSFGLILWEVARRCVSGGIV 450

  Fly   493 EEYKVPFYDVVPMDPSFEDMRKVVCIDNYRPSIPNRWSSDSLMTGMSKLMKECWHQNPDVRLPAL 557
            |||::|::|:||.|||:||||::|||...|||.|||||||..:..|.|||.|||..||..||.||
Human   451 EEYQLPYHDLVPSDPSYEDMREIVCIKKLRPSFPNRWSSDECLRQMGKLMTECWAHNPASRLTAL 515

  Fly   558 RIKKTIHKLASADE 571
            |:|||:.|::.:.:
Human   516 RVKKTLAKMSESQD 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sax	NP_001246193.1	Activin_recp	77..168	CDD:279413	20/106 (19%)
		TM_EGFR-like	182..218	CDD:213052	10/48 (21%)
		TGF_beta_GS	247..274	CDD:285687	17/26 (65%)
		STKc_ACVR1_ALK1	270..567	CDD:271044	171/296 (58%)
		TyrKc	276..553	CDD:197581	157/276 (57%)
BMPR1B	NP_001243722.1	Activin_recp	60..140	CDD:279413	21/108 (19%)
		STKc_BMPR1b	228..532	CDD:271121	171/302 (57%)
		S_TKc	235..519	CDD:214567	162/283 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D338017at33208
OrthoFinder	1	1.000	-	-		FOG0000203
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X151
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.820