Protein Alignment sax and Bmpr1b

DIOPT Version :10

• Sequence 1: NP_001246193.1
• Gene: sax / 35731
• FlyBaseID: FBgn0003317
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: XP_063138049.1
• Gene: Bmpr1b / 310914
• RGDID: 1595863
• Length: 550
• Species: Rattus norvegicus
• Alignment Length: 593
• Identity: 238/593 - (40%)
• Similarity: 327/593 - (55%)
• Gaps: 96/593 - (16%)

  Fly     3 SNIYLVFLLTFLLYNNARAEISDHLREDIPDLDMELSSASSAHLNGKELPAVPQNSVQTHPRRHI 67
            ||...:|||:  |::|:..:..|         :|.|.|:...::..|:     ::...|.|....
  Rat    27 SNCSGIFLLS--LWDNSLEKFVD---------NMLLRSSGKLNVGTKK-----EDGESTAPTARP 75

  Fly    68 KSKRRMKRRYKCYSCEPPCRDPYEFTHTCQNAIQCWKSRTRDADGQVQESRGCSTSPDQLPMICS 132
            |..|       | .|...|.:. ...:.|.....|:.....|..|....:.||
  Rat    76 KVLR-------C-KCHHHCPED-SVNNICSTDGYCFTMIEEDDSGTPVVTSGC------------ 119

  Fly   133 QNSLKING----------PSKRNTGKFVNVVCCA-GDYCNEGDFPELLPFDSNDVTVITADTSSI 186
               |.:.|          |.:|.     ::.||. .:.||:...|.|.|....|.
  Rat   120 ---LGLEGSDFQCRDTPIPHQRR-----SIECCTERNECNKDLHPTLPPLKDRDF---------- 166

  Fly   187 SKMLVAVLGPFLVIALLGAVT---------IFFIRRSHRKRLAASR----TKQDPEAYLVNDELL 238
                  |.||....|||.:||         |.|....::::.|..|    .:|| |.|:...|
  Rat   167 ------VDGPIHHKALLISVTVCSLLLVLIILFCYFRYKRQEARPRYSIGLEQD-ETYIPPGE-- 222

  Fly   239 RATSAGDSTLREYLQHSVTSGSGSGLPLLVQRTLAKQVTLIECIGRGKYGEVWRGHWHGESIAVK 303
                    :||:.::.|.:||||||||||||||:|||:.:::.||:|:|||||.|.|.||.:|||
  Rat   223 --------SLRDLIEQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRGEKVAVK 279

  Fly   304 IFFSRDEESWKRETEIYSTILLRHENILGFIGSDMTSRNSCTQLWLMTHYYPLGSLFDHLNRNAL 368
            :||:.:|.||.||||||.|:|:|||||||||.:|:....|.|||:|:|.|:..|||:|:|....|
  Rat   280 VFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTTL 344

  Fly   369 SHNDMVWICLSIANGLVHLHTEIFGKQGKPAMAHRDLKSKNILVTSNGSCVIADFGLAVTHSHVT 433
            ....|:.:..|..:||.|||||||..|||||:||||||||||||..||:|.|||.||||.....|
  Rat   345 DAKSMLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISDT 409

  Fly   434 GQLDLGNNPKVGTKRYMAPEVLDESIDLECFEALRRTDIYAFGLVLWEVCRRTISCGIAEEYKVP 498
            .::|:..|.:|||||||.|||||||::...|::....|:|:|||:|||:.||.:|.||.|||::|
  Rat   410 NEVDIPPNTRVGTKRYMPPEVLDESLNRTHFQSYIMADMYSFGLILWEIARRCVSGGIVEEYQLP 474

  Fly   499 FYDVVPMDPSFEDMRKVVCIDNYRPSIPNRWSSDSLMTGMSKLMKECWHQNPDVRLPALRIKKTI 563
            ::|:||.|||:||||::||:...|||.|||||||..:..|.|||.|||..||..||.|||:|||:
  Rat   475 YHDLVPSDPSYEDMREIVCMKKLRPSFPNRWSSDECLRQMGKLMTECWAHNPASRLTALRVKKTL 539

  Fly   564 HKLASADE 571
            .|::.:.:
  Rat   540 AKMSESQD 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sax	NP_001246193.1	TFP_LU_ECD_Sax	74..166	CDD:467129	17/102 (17%)
		TM_EGFR-like	182..218	CDD:213052	10/44 (23%)
		TGF_beta_GS	247..274	CDD:462503	17/26 (65%)
		STKc_ACVR1_ALK1	270..567	CDD:271044	169/296 (57%)
Bmpr1b	XP_063138049.1	None