Protein Alignment sax and tkv

DIOPT Version :10

• Sequence 1: NP_001246193.1
• Gene: sax / 35731
• FlyBaseID: FBgn0003317
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: XP_061510622.1
• Gene: tkv / 1271240
• VectorBaseID: AGAMI1_005334
• Length: 565
• Species: Anopheles gambiae
• Alignment Length: 584
• Identity: 237/584 - (40%)
• Similarity: 331/584 - (56%)
• Gaps: 60/584 - (10%)

  Fly     9 FLLTFLLYNNARAEISDHLREDIPDLDMELSS--ASSAHLNGKELPAVPQNSVQTHPRRHIKSKR 71
            |:| .||::......||.:.|.:...:..||.  ||:.|    :.||....:..|.......:..
Mosquito     7 FVL-LLLFSGGILAASDQVDELLAAAERPLSPPLASAEH----QPPAHDAGNNHTQEASLAAAIG 66

  Fly    72 RMKRRYKCYSCEPPCRDPYEFTHTCQN--AIQCWKSRTRDADGQVQE-----SRGCSTSPDQLPM 129
            ...|...|| ||..|....: ..||:.  ...|:.|.....|.:.::     |.|| .||:|...
Mosquito    67 STARVLTCY-CEGHCPGNLQ-NGTCETRPGGSCFVSVEAVLDEETKQLVPEYSHGC-MSPEQGGG 128

  Fly   130 ICSQNSLKINGPSKRNTGKFVNVVCCAG-DYCNEGDFPELLPFDSNDVTVITADTSSIS------ 187
            :.   ..|:...|.:..||  ::|||.. |.||:...|...|..:.......||.:|:.
Mosquito   129 LL---QCKVGTVSPQLHGK--SIVCCDNEDLCNQDLQPPYSPRTTTTPEPPLADPNSMHLFALTL 188

  Fly   188 KMLVAVLGPFLVIALLGAVTIFFIRRSHRKRLAASRTKQDPEAYLVNDELLRATSAGDSTLREYL 252
            .:.:.|.|   ::.||||....:.||..||           .|||:|.  |..|:.|...:.:.:
Mosquito   189 SVCLCVGG---LVVLLGAFFWVYRRREKRK-----------PAYLMNS--LYNTTNGHMPIADLV 237

  Fly   253 QHSVTSGSGSGLPLLVQRTLAKQVTLIECIGRGKYGEVWRGHWHGESIAVKIFFSRDEESWKRET 317
            :.  |||||||||||||||:|||:.::..:|:|:|||||...|..|.:||||||:.:|.||.|||
Mosquito   238 EQ--TSGSGSGLPLLVQRTIAKQIQMVHSVGKGRYGEVWLAKWRDEKVAVKIFFTTEESSWFRET 300

  Fly   318 EIYSTILLRHENILGFIGSDMTSRNSCTQLWLMTHYYPLGSLFDHLNRNALSHNDMVWICLSIAN 382
            |||.|:|:|:|||||||.:|:....|.||:.|:|.|:.||||.|:|.:..|:.:.:..:..|:|:
Mosquito   301 EIYQTVLMRNENILGFIAADIKGTGSWTQMLLITDYHELGSLHDYLQKRVLNPHMLKTLAHSLAS 365

  Fly   383 GLVHLHTEIFGKQGKPAMAHRDLKSKNILVTSNGSCVIADFGLAVTHSHVTGQLDLGNNPKVGTK 447
            |:.||||||||..|||::||||:|||||||..||.|.||||||||.::..:..:.:.||.:|||:
Mosquito   366 GVAHLHTEIFGTPGKPSIAHRDIKSKNILVKRNGQCAIADFGLAVKYTSESDTIQIANNSRVGTR 430

  Fly   448 RYMAPEVLDESIDLECFEALRRTDIYAFGLVLWEVCRR----------TISCGIAEEYKVPFYDV 502
            ||||||||.|::||..||..:..|:|:.|||.||:.||          |.:|   |:|.:|:.||
Mosquito   431 RYMAPEVLSETLDLNLFEGFKMADMYSVGLVFWEMARRCITTVRGAKNTTTC---EDYALPYQDV 492

  Fly   503 VPMDPSFEDMRKVVCIDNYRPSIPNRWSSDSLMTGMSKLMKECWHQNPDVRLPALRIKKTIHKL 566
            ||.|||||||..|||:...||.||.||..:.::..:||:|:||||.:|.|||.|||:|||:.||
Mosquito   493 VPSDPSFEDMYAVVCVKGVRPPIPQRWQDEDILVVLSKIMQECWHPSPAVRLTALRVKKTLVKL 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sax	NP_001246193.1	TFP_LU_ECD_Sax	74..166	CDD:467129	27/99 (27%)
		TM_EGFR-like	182..218	CDD:213052	11/41 (27%)
		TGF_beta_GS	247..274	CDD:462503	15/26 (58%)
		STKc_ACVR1_ALK1	270..567	CDD:271044	160/307 (52%)
tkv	XP_061510622.1	None