Protein Alignment sax and babo

DIOPT Version :10

• Sequence 1: NP_001246193.1
• Gene: sax / 35731
• FlyBaseID: FBgn0003317
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: XP_061512200.1
• Gene: babo / 1269085
• VectorBaseID: AGAMI1_014139
• Length: 663
• Species: Anopheles gambiae
• Alignment Length: 603
• Identity: 244/603 - (40%)
• Similarity: 341/603 - (56%)
• Gaps: 78/603 - (12%)

  Fly     1 MESNIYLVFLLTFLLYNNARAE-ISDHLRED---------------IPDLDMELSSASSAHLNGK 49
            :.:.:.|:.|.:|..::.|:|. |..|..:|               .|....:.||::.....|.
Mosquito   101 LSAALVLLLLPSFSDWSFAKASTIHRHTADDNDTSPSAGVQQAKDQQPPTGKQHSSSTENGAGGG 165

  Fly    50 ELPAVPQN----SVQTHPRRHIKSKRRMKRRYKCYSCEPPCRDPYEFTHTCQNAIQCWKSRTRDA 110
            .....|.:    |.||......|:|.::   .||: |: .|:|.   ...|:....|:.|.||:|
Mosquito   166 AGALAPASLQAASPQTMTLTADKNKTKL---LKCH-CD-ICKDE---NFVCETDGLCFTSLTREA 222

  Fly   111 DGQVQESRGCSTSPDQLPMICSQNSLKIN-GP-------SKRNTGKFVNVVCCAGDYCNEGDFP- 166
            ||.::.|..|.             .||.: ||       :|...|...:..|...|.||....|
Mosquito   223 DGTLKYSYRCF-------------DLKYHLGPFTWNWCRNKTENGTNDHYCCYGPDLCNLSLKPA 274

  Fly   167 ----ELLPFDSNDVTVITADTSSISKMLVAVLGPFLVIALLGAVTIFFIRRSHRKRLAASRTKQD 227
                |....:|..:..|         :|:.::...|::||...|.:.    ..|||.:.:|
Mosquito   275 TPMVEAQKEESYGLRWI---------LLLTIVAVMLLLALFVGVLML----GRRKRNSGAR---- 322

  Fly   228 PEAYLVNDELLRATSA---GDSTLREYLQHSVTSGSG-SGLPLLVQRTLAKQVTLIECIGRGKYG 288
              ..|..|.|..|:..   |.:|::..::.| ||||| |||||||||::|:|:.|::.||:|::|
Mosquito   323 --QILPEDSLCGASYPILNGHTTIQGLIEMS-TSGSGSSGLPLLVQRSIARQIQLVDVIGKGRFG 384

  Fly   289 EVWRGHWHGESIAVKIFFSRDEESWKRETEIYSTILLRHENILGFIGSDMTSRNSCTQLWLMTHY 353
            |||||.|.||::|||||.||:|.||.||.|||.||:||||||||||.:|.....:.|||||:|.|
Mosquito   385 EVWRGRWRGENVAVKIFSSREECSWSREAEIYQTIMLRHENILGFIAADNKDNGTWTQLWLVTDY 449

  Fly   354 YPLGSLFDHLNRNALSHNDMVWICLSIANGLVHLHTEIFGKQGKPAMAHRDLKSKNILVTSNGSC 418
            :..|||||.|....:..:.|:.:..|||.||.|||.:|.|.:||||:||||||||||||.||.:|
Mosquito   450 HENGSLFDFLTARCVDPDTMLEMAFSIATGLAHLHMDIVGTRGKPAIAHRDLKSKNILVKSNLTC 514

  Fly   419 VIADFGLAVTHSHVTGQLDLGNNPKVGTKRYMAPEVLDESIDLECFEALRRTDIYAFGLVLWEVC 483
            .|.|.||||.|...|..:|..:..:||||||||||||||:|::..|::.:|.|:||.||||||:.
Mosquito   515 CIGDLGLAVRHIVATDTVDQPSTHRVGTKRYMAPEVLDETINVSQFDSFKRADVYALGLVLWEIA 579

  Fly   484 RRTISCGIAEEYKVPFYDVVPMDPSFEDMRKVVCIDNYRPSIPNRWSSDSLMTGMSKLMKECWHQ 548
            ||....|:.:||::||||||..||:.|:||||||:|.:|||||:||.:...:..:||:|||||:|
Mosquito   580 RRCNVDGVYDEYQMPFYDVVQPDPTIEEMRKVVCVDQHRPSIPSRWIACDTLHAISKVMKECWYQ 644

  Fly   549 NPDVRLPALRIKKTIHKL 566
            :|..||.:||||||:..|
Mosquito   645 HPAARLSSLRIKKTLANL 662

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sax	NP_001246193.1	TFP_LU_ECD_Sax	74..166	CDD:467129	25/99 (25%)
		TM_EGFR-like	182..218	CDD:213052	6/35 (17%)
		TGF_beta_GS	247..274	CDD:462503	16/27 (59%)
		STKc_ACVR1_ALK1	270..567	CDD:271044	168/297 (57%)
babo	XP_061512200.1	None