DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment sax and Bmpr1b

DIOPT Version :10

Sequence 1:NP_001246193.1 Gene:sax / 35731 FlyBaseID:FBgn0003317 Length:582 Species:Drosophila melanogaster
Sequence 2:NP_031586.1 Gene:Bmpr1b / 12167 MGIID:107191 Length:502 Species:Mus musculus


Alignment Length:518 Identity:223/518 - (43%)
Similarity:300/518 - (57%) Gaps:73/518 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    78 KCYSCEPPCRDPYEFTHTCQNAIQCWKSRTRDADGQVQESRGCSTSPDQLPMICSQNSLKING-- 140
            :| .|...|.:. ...:.|.....|:.....|..|....:.||               |.:.|  
Mouse    31 RC-KCHHHCPED-SVNNICSTDGYCFTMIEEDDSGMPVVTSGC---------------LGLEGSD 78

  Fly   141 --------PSKRNTGKFVNVVCCA-GDYCNEGDFPELLPFDSNDVTVITADTSSISKMLVAVLGP 196
                    |.:|.     ::.||. .:.||:...|.|.|....|.                |.||
Mouse    79 FQCRDTPIPHQRR-----SIECCTERNECNKDLHPTLPPLKDRDF----------------VDGP 122

  Fly   197 FLVIALLGAVT---------IFFIRRSHRKRLAASR----TKQDPEAYLVNDELLRATSAGDSTL 248
            ....|||.:||         |.|....::::.|..|    .:|| |.|:...|          :|
Mouse   123 IHHKALLISVTVCSLLLVLIILFCYFRYKRQEARPRYSIGLEQD-ETYIPPGE----------SL 176

  Fly   249 REYLQHSVTSGSGSGLPLLVQRTLAKQVTLIECIGRGKYGEVWRGHWHGESIAVKIFFSRDEESW 313
            |:.::.|.:||||||||||||||:|||:.:::.||:|:|||||.|.|.||.:|||:||:.:|.||
Mouse   177 RDLIEQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEASW 241

  Fly   314 KRETEIYSTILLRHENILGFIGSDMTSRNSCTQLWLMTHYYPLGSLFDHLNRNALSHNDMVWICL 378
            .||||||.|:|:|||||||||.:|:....|.|||:|:|.|:..|||:|:|....|....|:.:..
Mouse   242 FRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDAKSMLKLAY 306

  Fly   379 SIANGLVHLHTEIFGKQGKPAMAHRDLKSKNILVTSNGSCVIADFGLAVTHSHVTGQLDLGNNPK 443
            |..:||.|||||||..|||||:||||||||||||..||:|.|||.||||.....|.::|:..|.:
Mouse   307 SSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISDTNEVDIPPNTR 371

  Fly   444 VGTKRYMAPEVLDESIDLECFEALRRTDIYAFGLVLWEVCRRTISCGIAEEYKVPFYDVVPMDPS 508
            |||||||.|||||||::...|::....|:|:|||:|||:.||.:|.||.|||::|::|:||.|||
Mouse   372 VGTKRYMPPEVLDESLNRNHFQSYIMADMYSFGLILWEIARRCVSGGIVEEYQLPYHDLVPSDPS 436

  Fly   509 FEDMRKVVCIDNYRPSIPNRWSSDSLMTGMSKLMKECWHQNPDVRLPALRIKKTIHKLASADE 571
            :||||::||:...|||.|||||||..:..|.|||.|||.|||..||.|||:|||:.|::.:.:
Mouse   437 YEDMREIVCMKKLRPSFPNRWSSDECLRQMGKLMTECWAQNPASRLTALRVKKTLAKMSESQD 499

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
saxNP_001246193.1 TFP_LU_ECD_Sax 74..166 CDD:467129 17/98 (17%)
TM_EGFR-like 182..218 CDD:213052 10/44 (23%)
TGF_beta_GS 247..274 CDD:462503 17/26 (65%)
STKc_ACVR1_ALK1 270..567 CDD:271044 170/296 (57%)
Bmpr1bNP_031586.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..24
TFP_LU_ECD_BMPR1B 28..113 CDD:467133 19/103 (18%)
STKc_BMPR1b 198..502 CDD:271121 170/302 (56%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.