Protein Alignment sax and Bmpr1a

DIOPT Version :9

• Sequence 1: NP_001246193.1
• Gene: sax / 35731
• FlyBaseID: FBgn0003317
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_033888.2
• Gene: Bmpr1a / 12166
• MGIID: 1338938
• Length: 532
• Species: Mus musculus
• Alignment Length: 574
• Identity: 232/574 - (40%)
• Similarity: 316/574 - (55%)
• Gaps: 104/574 - (18%)

  Fly    44 AHLNGKELPAV--------------PQNSVQTHPRRHIKSKRRMKRRYKCYSCEPPCRDPYEFTH 94
            :|:.|:.|.::              |:|.|...|...:..       .||| |...|.|. ...:
Mouse    19 SHVQGQNLDSMLHGTGMKSDLDQKKPENGVTLAPEDTLPF-------LKCY-CSGHCPDD-AINN 74

  Fly    95 TCQNAIQCWKSRTRDADGQVQESRGCSTSPDQLPMICSQNSLKING----------PSKRNTGKF 149
            ||.....|:.....|..|:...:.||               :|..|          ...|.|
Mouse    75 TCITNGHCFAIIEEDDQGETTLTSGC---------------MKYEGSDFQCKDSPKAQLRRT--- 121

  Fly   150 VNVVCCAGDYCNEGDFPELLPFDSNDVTVITADTSSISKMLVAVLGPF-------LVIALLGAVT 207
              :.||..:.||:...|.|.|                     .|:|||       ||:.:..||.
Mouse   122 --IECCRTNLCNQYLQPTLPP---------------------VVIGPFFDGSIRWLVVLISMAVC 163

  Fly   208 IF--------FIRRSHRKRLAA----SRTKQDPEAYLVNDELLRATSAGDSTLREYLQHSVTSGS 260
            |.        |..:.:.|.:::    :|..:..||::         ..|:| |::.:..|.:|||
Mouse   164 IVAMIIFSSCFCYKHYCKSISSRGRYNRDLEQDEAFI---------PVGES-LKDLIDQSQSSGS 218

  Fly   261 GSGLPLLVQRTLAKQVTLIECIGRGKYGEVWRGHWHGESIAVKIFFSRDEESWKRETEIYSTILL 325
            |||||||||||:|||:.::..:|:|:|||||.|.|.||.:|||:||:.:|.||.||||||.|:|:
Mouse   219 GSGLPLLVQRTIAKQIQMVRQVGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLM 283

  Fly   326 RHENILGFIGSDMTSRNSCTQLWLMTHYYPLGSLFDHLNRNALSHNDMVWICLSIANGLVHLHTE 390
            |||||||||.:|:....|.|||:|:|.|:..|||:|.|....|....::.:..|.|.||.|||||
Mouse   284 RHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDFLKCATLDTRALLKLAYSAACGLCHLHTE 348

  Fly   391 IFGKQGKPAMAHRDLKSKNILVTSNGSCVIADFGLAVTHSHVTGQLDLGNNPKVGTKRYMAPEVL 455
            |:|.|||||:|||||||||||:..||||.|||.||||..:..|.::|:..|.:||||||||||||
Mouse   349 IYGTQGKPAIAHRDLKSKNILIKKNGSCCIADLGLAVKFNSDTNEVDIPLNTRVGTKRYMAPEVL 413

  Fly   456 DESIDLECFEALRRTDIYAFGLVLWEVCRRTISCGIAEEYKVPFYDVVPMDPSFEDMRKVVCIDN 520
            |||::...|:.....|||:|||::||:.||.|:.||.|||::|:|::||.|||:||||:|||:..
Mouse   414 DESLNKNHFQPYIMADIYSFGLIIWEMARRCITGGIVEEYQLPYYNMVPSDPSYEDMREVVCVKR 478

  Fly   521 YRPSIPNRWSSDSLMTGMSKLMKECWHQNPDVRLPALRIKKTIHKLA-SADEKI 573
            .||.:.|||:||..:..:.|||.|||..||..||.|||||||:.|:. |.|.||
Mouse   479 LRPIVSNRWNSDECLRAVLKLMSECWAHNPASRLTALRIKKTLAKMVESQDVKI 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sax	NP_001246193.1	Activin_recp	77..168	CDD:279413	22/100 (22%)
		TM_EGFR-like	182..218	CDD:213052	10/50 (20%)
		TGF_beta_GS	247..274	CDD:285687	16/26 (62%)
		STKc_ACVR1_ALK1	270..567	CDD:271044	167/296 (56%)
		TyrKc	276..553	CDD:197581	152/276 (55%)
Bmpr1a	NP_033888.2	Activin_recp	63..132	CDD:395845	17/89 (19%)
		Mediates specificity for BMP ligand. /evidence=ECO:0000250	107..109		0/1 (0%)
		TGF_beta_GS	205..232	CDD:400699	17/27 (63%)
		STKc_BMPR1a	238..524	CDD:271122	161/285 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D338017at33208
OrthoFinder	1	1.000	-	-		FOG0000203
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X151
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.820